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London Irish will look to capitalise on recent form and pull away from their relegation rivals when they face Worcester in the Aviva Premiership.
The Exiles have won six of their last 10 outings as they start to move away from bottom club London Welsh and build momentum.
Worcester were 35-11 victors when the sides met in the fifth round of the season and the Warriors will look to complete their first league double over the Exiles on Saturday.
However, they take to the road having not won away from home since New Year's Day 2012.
In contrast the hosts have won their last four games at the Madejski Stadium while Worcester have not managed to secure victory away to the Exiles since 2005.
Lock George Skivington, who has signed a new contract, will captain London Irish with Bryn Evans, Matt Gervey, Ofisa Treviranus and Hala'ufia all joining him in the pack.
Shane Geraghty and Guy Armitage are partnered together in the centres while Jonathan Joseph returns from injury to be named amongst the Exiles' replacements.
Paul Hodgson is selected at scrum-half for the Warriors as he faces the Exiles for the first time since leaving Sixways.
Worcester coach Richard Hill has made just one change in the forward line, John Andress replacing Euan Murray at tighthead prop.
Chris Jones and Semisi Taulava have both passed fitness tests and feature amongst the replacements for the Sixways side.
London Irish: 15 Tom Homer, 14 Topsy Ojo, 13 Guy Armitage, 12 Shane Geraghty, 11 Marland Yarde, 10 Ian Humphreys, 9 Pat Phibbs, 8 Chris Hala'ufia, 7 Ofisa Treviranus, 6 Matt Garvey, 5 Bryn Evans, 4 George Skivington (capt), 3 Halani Aulika, 2 David Paice, 1 Max Lahiff.
Replacements: 16 Scott Lawson, 17 Jerry Yanuyanutawa, 18 Leo Halavatau, 19 Jamie Gibson, 20 Jon Fisher, 21 Sailosi Tagicakibau, 22 Jonathan Joseph, 23 Jack Moates.
Worcester Warriors:15 Chris Pennell, 14 Josh Drauniniu, 13 Alex Grove, 12 Jon Clarke, 11 David Lemi, 10 Andy Goode, 9 Paul Hodgson, 8 Blair Cowan, 7 Matt Kvesic, 6 Neil Best, 5 Dean Schofield, 4 James Percival (capt), 3 John Andress, 2 Ed Shervington, 1 Matt Mullan.
Replacements: 16 Aleki Lutui, 17 Ceri Jones, 18 Euan Murray, 19 Chris Jones, 20 Semisi Taulava, 21 Jonny Arr, 22 Danny Gray, 23 Josh Matavesi.
|Click here for more betting|
|Friday 2nd May|
|19:45||Bath vs Northampton|
|Saturday 3rd May|
|15:00||Saracens vs Worcester|
|15:00||Wasps vs Newcastle|
|15:00||Gloucester vs London Irish|
|15:15||Sale vs Leicester|
|Sunday 4th May|
|14:00||Exeter vs Harlequins|
|Saturday 10th May|
|15:15||Newcastle vs Exeter|
|15:15||Northampton vs Wasps|
|15:15||Worcester vs Gloucester|
|15:15||Leicester vs Saracens|
|15:15||Harlequins vs Bath|
|15:15||London Irish vs Sale|
|Sunday 20th April|
|Newcastle 18 - 23 Saracens|
|Northampton 36 - 21 London Irish|
|Saturday 19th April|
|Wasps 38 - 30 Gloucester|
|Bath 32 - 20 Worcester|
|Exeter 12 - 55 Sale|
|Friday 18th April|
|Harlequins 24 - 20 Leicester|
|Sunday 13th April|
|London Irish 40 - 12 Newcastle|
|Saracens 28 - 24 Northampton|
|Saturday 12th April|
|Gloucester 17 - 18 Bath|
|Worcester 33 - 38 Exeter|
|Leicester 27 - 15 Wasps|
|Friday 11th April|
|Sale Sharks 12 - 27 Harlequins|
|Sunday 30th March|
|Newcastle 12 - 17 Worcester|
|Saturday 29th March|
|Northampton 16 - 22 Leicester|
|Wasps 20 - 32 Saracens|
|Exeter 13 - 14 Gloucester|
|Harlequins 23 - 9 London Irish|
|Friday 28th March|
|Bath 11 - 12 Sale Sharks|
|Sunday 23rd March|
|Leicester 45 - 15 Exeter|
|Saturday 22nd March|
|London Irish 23 - 44 Bath|
|Saracens 39 - 17 Harlequins|
|Gloucester 40 - 33 Newcastle|
|Sale Sharks 19 - 6 Northampton|
|Friday 21st March|
|Worcester 11 - 13 Wasps|
Read the thoughts and opinions of Stuart Barnes with skysports.com