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Gloucester have made five changes ahead of their Aviva Premiership clash against league leaders Saracens at Kingsholm on Saturday.
Director of Rugby Nigel Davies makes front and back line changes in an attempt to keep Gloucester's play-off ambitions alive.
Injuries sustained by Huia Edmonds and Dario Chistolini at Sale last week mean Koree Britton and Shaun Knight start in the front row.
The changes see Tom Savage move into the second row as well as assume the captaincy while Sione Kalamafoni starts in the flanks with Ben Morgan wearing the number eight jersey on his return after spending four months out.
In the backs Charlie Sharples returns to the right wing while Henry Trinder gets the nod ahead of Mike Tindall at centre where he will partner Billy Twelvetrees.
Meanwhile top-of-the-table Saracens travel to Gloucester with six changes in personnel with an international trio rested with the play-offs in sight.
Mark McCall has opted to start Owen Farrell at centre while Richard Wigglesworth returns to the side at scrum-half.
Captain Steve Borthwick, Alistair Hargreaves, Will Fraser and Ernst Joubert all return to the pack following absences.
England backs Chris Ashton and Brad Barritt both sit out of the visit to Gloucester as does Scotland forward Kelly Brown.
Gloucester enter the clash five points adrift of the play-off places while Saracens hold a comfortable four-point advantage at the head of the table.
Saracens: 15 Alex Goode, 14 Chris Wyles, 13 Joel Tomkins, 12 Owen Farrell, 11 David Strettle, 10 Charlie Hodgson, 9 Richard Wigglesworth, 8 Ernst Joubert, 7 Will Fraser, 6 Jackson Wray, 5 Alistair Hargreaves, 4 Steve Borthwick (capt), 3 Matt Stevens, 2 John Smit, 1 Rhys Gill.
Replacements:16 Jamie George, 17 Mako Vunipola, 18 Carlos Nieto, 19 George Kruis, 20 Jacques Burger, 21 Ben Spencer, 22 Duncan Taylor, 23 Joe Maddock.
Gloucester:15 Rob Cook, 14 Charlie Sharples, 13 Henry Trinder, 12 Billy Twelvetrees, 11 Jonny May, 10 Freddie Burns, 9 Dan Robson, 8 Nick Wood, 7 Koree Britton, 6 Shaun Knight, 5 Tom Savage (capt), 4 Lua Lokotui, 3 Sione Kalamafoni, 2 Akapusi Qera, 1 Ben Morgan.
Replacements:16 Tommaso d'Apice, 17 Dan Murphy, 18 Yann Thomas, 19 Peter Buxton, 20 Andy Hazell, 21 Dave Lewis, 22 Ryan Mills, 23 Martyn Thomas.
"You have to give Saracens credit, they're a very efficient side. They know what they do, and they do it very well.
"We have to be on our mettle on Saturday. We have to be clear about what our game plan is. The real battle will be about the gain line both with and without the ball, and both teams will be looking to win that battle. It's going to be a physical encounter."
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|Friday 21st March|
|19:45||Worcester vs Wasps|
|Saturday 22nd March|
|14:00||Sale vs Northampton|
|15:00||Gloucester vs Newcastle|
|15:15||Saracens vs Harlequins|
|17:30||London Irish vs Bath|
|Sunday 23rd March|
|14:00||Leicester vs Exeter|
|Friday 28th March|
|19:45||Bath vs Sale|
|Saturday 29th March|
|15:00||Wasps vs Saracens|
|15:00||Harlequins vs London Irish|
|15:00||Exeter vs Gloucester|
|15:15||Northampton vs Leicester|
|Sunday 30th March|
|14:00||Newcastle vs Worcester|
|Friday 11th April|
|19:45||Sale vs Harlequins|
|Saturday 12th April|
|15:00||Worcester vs Exeter|
|15:00||Leicester vs Wasps|
|15:15||Gloucester vs Bath|
|Sunday 13th April|
|14:00||Saracens vs Northampton|
|15:00||London Irish vs Newcastle|
|Friday 18th April|
|19:45||Harlequins vs Leicester|
|Saturday 19th April|
|15:00||Bath vs Worcester|
|15:00||Exeter vs Sale Sharks|
|15:15||Wasps vs Gloucester|
|Sunday 20th April|
|14:00||Northampton vs London Irish|
|15:00||Newcastle vs Saracens|
|Saturday 3rd May|
|15:00||Bath vs Northampton|
|Sunday 2nd March|
|Newcastle 18 - 41 Leicester|
|Saturday 1st March|
|Northampton 39 - 13 Gloucester|
|Exeter 18 - 0 London Irish|
|Harlequins 21 - 20 Worcester|
|Wasps 17 - 21 Sale Sharks|
|Friday 28th February|
|Bath 10 - 23 Saracens|
|Sunday 23rd February|
|Saracens 23 - 10 Exeter|
|Newcastle 16 - 22 Northampton|
|London Irish 15 - 20 Leicester|
|Saturday 22nd February|
|Worcester 12 - 24 Sale Sharks|
|Bath 32 - 25 Wasps|
|Gloucester 25 - 20 Harlequins|
|Sunday 16th February|
|Leicester 11 - 8 Gloucester|
|Saturday 15th February|
|Exeter 23 - 27 Bath|
|Wasps 20 - 23 London Irish|
|Northampton 30 - 14 Worcester|
|Harlequins 18 - 14 Newcastle|
|Friday 14th February|
|Sale Sharks 10 - 15 Saracens|
|Sunday 9th February|
|Harlequins 11 - 10 Wasps|
|Saturday 8th February|
|Exeter 16 - 17 Northampton|
|Saracens 13 - 22 London Irish|
|Bath 24 - 6 Newcastle|
|Friday 7th February|
|Sale Sharks 24 - 19 Gloucester|
|Worcester 22 - 23 Leicester|
Read the thoughts and opinions of Stuart Barnes with skysports.com