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Harlequins will field the same side that won last year's Premiership final as they look to book their return to the play-offs with a win over Worcester at Sixways.
Quins boss Conor O'Shea names his title-winning XV for the first time this season, knowing that a win will book their play-off place after they ended a run of three successive defeats last week by beating Bath.
James Johnston will make his 100th appearance for the club and is named in the front-row with Joe Gray and Joe Marler, while George Robson has recovered from a knock he picked up last week and starts in the second-row, while Nick Easter, who starts at number eight, will make his 200th appearance for the club.
There are two changes in the backline from the side that defeated Bath last weekend as Jordan Turner-Hall is named at inside centre, while Ugo Monye starts on the left wing.
Matt Hopper had surgery on a finger injury on Monday and will be out for 14 weeks, while Tom Casson is still struggling with a knee injury sustained against Munster.
Worcester have lost eight out of their last nine games and have been beaten by Harlequins in each of their last 11 meetings, but will hope to end that streak in what will be Andy Goode's last appearance at Sixways before he joins Wasps.
Worcester wing Ben Howard will make his first Premiership start and Jon Clarke is named at inside centre in place of the suspended Josh Matavesi.
Matt Mullan and Matt Kvesic will also be making their final Sixways appearances for the Warriors before moving to Gloucester and London Wasps respectively.
Craig Gillies and Shaun Perry are recalled to the bench as Warriors search for their sixth Premiership win of the season.
Worcester: 15 Chris Pennell, 14 Josh Drauniniu, 13 Alex Grove, 12 Jon Clarke, 11 Ben Howard, 10 Andy Goode, 9 Jonny Arr, 8 Semisi Taulava, 7 Matt Kvesic, 6 Neil Best, 5 Chris Jones, 4 James Percival (c), 3 Euan Murray, 2 Ed Shervington, 1 Matt Mullan.
Replacements: 16 Aleki Lutui, 17 Rob O'Donnell, 18 John Andress, 19 Craig Gillies, 20 Jake Abbott, 21 Shaun Perry, 22 Danny Gray, 23 Joe Carlisle.
Harlequins: 15 Mike Brown, 14 Tom Williams, 13 George Lowe, 12 Jordan Turner-Hall, 11 Ugo Monye, 10 Nick Evans, 9 Danny Care, 8 Nick Easter, 7 Chris Robshaw, 6 Maurie Fa'asavalu, 5 George Robson, 4 Olly Kohn, 3 James Johnston, 2 Joe Gray, 1 Joe Marler.
Replacements: 16 Rob Buchanan, 17 Mark Lambert, 18 Will Collier, 19 Charlie Matthews, 20 Tom Guest,, 21 Karl Dickson, 22 Ben Botica, 23 Ross Chisholm.
Worcester coach Nigel Redman
"We have picked a team with a lot of Worcester influence and we want the players to give that extra bit. If they all do that, it will be enough.
"It's important for everyone concerned that we play with intent. Every game is a fresh occasion and a new opportunity and we will play with a positive mindset and aim to win the game.
"We have been competitive in most matches this season. Sometimes we have come up short and we are all responsible for that. When you look at our performances in some of our matches, we have looked like a very good team.
"We expect Harlequins to arrive at Sixways and play like champions. They won the Aviva Premiership title last season and will come here looking to secure a top four place."
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|Friday 21st March|
|19:45||Worcester vs Wasps|
|Saturday 22nd March|
|14:00||Sale vs Northampton|
|15:00||Gloucester vs Newcastle|
|15:15||Saracens vs Harlequins|
|17:30||London Irish vs Bath|
|Sunday 23rd March|
|14:00||Leicester vs Exeter|
|Friday 28th March|
|19:45||Bath vs Sale|
|Saturday 29th March|
|15:00||Wasps vs Saracens|
|15:00||Harlequins vs London Irish|
|15:00||Exeter vs Gloucester|
|15:15||Northampton vs Leicester|
|Sunday 30th March|
|14:00||Newcastle vs Worcester|
|Friday 11th April|
|19:45||Sale vs Harlequins|
|Saturday 12th April|
|15:00||Worcester vs Exeter|
|15:00||Leicester vs Wasps|
|15:15||Gloucester vs Bath|
|Sunday 13th April|
|14:00||Saracens vs Northampton|
|15:00||London Irish vs Newcastle|
|Friday 18th April|
|19:45||Harlequins vs Leicester|
|Saturday 19th April|
|15:00||Bath vs Worcester|
|15:00||Exeter vs Sale Sharks|
|15:15||Wasps vs Gloucester|
|Sunday 20th April|
|14:00||Northampton vs London Irish|
|15:00||Newcastle vs Saracens|
|Saturday 3rd May|
|15:00||Bath vs Northampton|
|Sunday 2nd March|
|Newcastle 18 - 41 Leicester|
|Saturday 1st March|
|Northampton 39 - 13 Gloucester|
|Exeter 18 - 0 London Irish|
|Harlequins 21 - 20 Worcester|
|Wasps 17 - 21 Sale Sharks|
|Friday 28th February|
|Bath 10 - 23 Saracens|
|Sunday 23rd February|
|Saracens 23 - 10 Exeter|
|Newcastle 16 - 22 Northampton|
|London Irish 15 - 20 Leicester|
|Saturday 22nd February|
|Worcester 12 - 24 Sale Sharks|
|Bath 32 - 25 Wasps|
|Gloucester 25 - 20 Harlequins|
|Sunday 16th February|
|Leicester 11 - 8 Gloucester|
|Saturday 15th February|
|Exeter 23 - 27 Bath|
|Wasps 20 - 23 London Irish|
|Northampton 30 - 14 Worcester|
|Harlequins 18 - 14 Newcastle|
|Friday 14th February|
|Sale Sharks 10 - 15 Saracens|
|Sunday 9th February|
|Harlequins 11 - 10 Wasps|
|Saturday 8th February|
|Exeter 16 - 17 Northampton|
|Saracens 13 - 22 London Irish|
|Bath 24 - 6 Newcastle|
|Friday 7th February|
|Sale Sharks 24 - 19 Gloucester|
|Worcester 22 - 23 Leicester|
Read the thoughts and opinions of Stuart Barnes with skysports.com