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Shane Jennings will captain Leinster in their PRO12 clash against the Scarlets at Parc y Scarlets on Saturday.
Jennings is joined in the back-row by fellow flanker Dominic Ryan and number eight Leo Auva'a, while Damian Browne locks down alongside Devin Toner.
Isaac Boss, who skippered the side in last weekend's 10-all draw away to Sale Sharks, partners Ian Madigan at half-back.
23-year-old fly-half Madigan, who was the province's Young Player of the Year last season, will make his 50th appearance after featuring 26 times last season.
Noel Reid continues his centre partnership with Brendan Macken, with Andrew Conway named in a pacey back three alongside Fionn Carr and full-back Isa Nacewa.
Tom Denton could be set to make his competitive debut for the team if he appears from the bench which includes six products from the Leinster Academy.
Meanwhile, the Scarlets are showing their intent with a strong team and plenty of experience and power to call on from the replacements bench.
There will be plenty to excite the home supporters in the backs with Wales internationals Liam Williams, George North and Scott Williams on hand.
They are backed by experienced league campaigners Andy Fenby, Gareth Maule and Aled Thomas, all of whom put in strong performances in their pre-season clash against London Welsh last weekend.
Aaron Shingler returns to the back-row alongside Josh Turnbull and new skipper Rob McCusker at number eight, with new South African signing George Earle.
Former Osprey Richard Kelly occupies the second row after the Scarlets produced a strong line-out performance last weekend.
With internationals Matthew Rees, Rhys Priestland and Jon Davies on the bench, the Scarlets have plenty of experience and flair to draw on for this encounter.
Scarlets:15 Liam Williams, 14 George North, 13 Gareth Maule, 12 Scott Williams, 11 Andy Fenby, 10 Aled Thomas, 9 Tavis Knoyle, 8 Rob McCusker (c), 7 Josh Turnbull, 6 Aaron Shingler, 5 Richard Kelly, 4 George Earle, 3 Deacon Manu, 2 Ken Owens, 1 Rhodri Jones.
Replacements: 16 Matthew Rees, 17 Phil John, 18 Samson Lee, 19 Sione Timani, 20 Kieran Murphy, 21 Gareth Davies, 22 Rhys Priestland, 23 Jonathan Davies.
Leinster: 15 Isa Nacewa, 14 Andrew Conway, 13 Brendan Macken, 12 Noel Reid, 11 Fionn Carr, 10 Ian Madigan, 9 Isaac Boss, 8 Leo Auva'a, 7 Shane Jennings (c), 6 Dominic Ryan, 5 Devin Toner, 4 Damian Browne, 3 Jamie Hagan, 2 Richardt Strauss, 1 Heinke van der Merwe.
Replacements: 16 Aaron Dundon, 17 Jack McGrath, 18 Martin Moore, 19 Tom Denton, 20 Jordi Murphy, 21 John Cooney, 22 Collie O'Shea, 23 Darren Hudson.
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|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Glasgow vs Zebre|
|Sunday 20th April|
|Newport Gwent D'gons 10 - 20 Ospreys|
|Cardiff Blues 17 - 13 Scarlets|
|Saturday 19th April|
|Connacht 23 - 32 Munster|
|Zebre 26 - 13 Edinburgh|
|Friday 18th April|
|Glasgow 27 - 9 Ulster|
|Leinster 62 - 7 Benetton Treviso|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
Read the thoughts and opinions of Stuart Barnes with skysports.com