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|Home team||Away Team|
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Two winless teams go head-to-head on Friday night as champions Ospreys take on the Glasgow Warriors at Liberty Stadium.
Ospreys followed up their opening weekend loss to Benetton by losing at home to Ulster earlier this month.
The Warriors have not fared any better, suffering back-to-back defeats to Ulster and Scarlets.
The omens are good for Glasgow as they have lost just one of their last nine matches against the Welsh regions.
Left wing Tom Grabham will make his first competitive start for the Ospreys in Friday's PRO12 clash.
The likes of Ryan Jones, Eli Walker, James Goode, Tom Habberfield, Tom Isaacs, James King, Tom Smith, Jonathan Thomas, Adam Jones are all ruled out due to injury.
Ospreys head coach Steve Tandy believes a win is vital for his troops.
"This is an important game for us, against a very good, very powerful and very dangerous Glasgow team. Like us they'll be disappointed at the start they've had, but we know they are a real threat," he said.
"They were in the PRO12 semis last season, as they were two years ago, and just as we haven't become a bad team on the back of two defeats neither have they.
"We aren't that far away from where we want to be, but in reality we need big improvements in application, discipline and accuracy if we are going to turn possession and chances into wins."
There are six changes to Glasgow's starting XV that ran out against the Scarlets.
With Pat MacArthur nursing a fractured foot and Moray Low a calf complaint, Dougie Hall starts at hooker and Mike Cusack at tight-head prop. In the back-row, John Barclay moves to blindside flanker with Chris Fusaro coming in at openside.
The backline switches see Duncan Weir replace Ruaridh Jackson at stand-off, Tommy Semour get the nod over Sean Lamont on the right wing, and Peter Horne (pictured) start at inside centre.
Head coach Gregor Townsend explained: "As a coaching group, we strongly believe this team has the necessary attributes to win Friday's game.
"We're sending out an experienced pack, and are happy with the balance of the combinations in there.
"We know this is going to be another very challenging match, but as a group, we're primed to deliver the result that we and our supporters all want."
Ospreys: 15 Richard Fussell, 14 Hanno Dirksen, 13 Jonathan Spratt, 12 Ashley Beck, 11 Tom Grabham, 10 Dan Biggar, 9 Rhys Webb, 8 Joe Bearman, 7 Justin Tipuric (c), 6 George Stowers, 5 Ian Evans, 4 Ian Gough, 3 Aaron Jarvis, 2 Richard Hibbard, 1 Duncan Jones.
Replacements: 16 Scott Baldwin, 17 Ryan Bevington, 18 Joe Rees, 19 Alun Wyn Jones, 20 Sam Lewis, 21 Kahn Fotuali'i, 22 Matthew Morgan, 23 Andrew Bishop.
Glasgow Warriors:15 Peter Murchie, 14 Tommy Seymour, 13 Alex Dunbar, 12 Peter Horne, 11 DTH van der Merwe, 10 Duncan Weir, 9 Chris Cusiter, 8 Ryan Wilson, 7 Chris Fusaro, 6 John Barclay, 5 Al Kellock (c), 4 Tom Ryder, 3 Mike Cusack, 2 Dougie Hall, 1 Ryan Grant.
Replacements: 16 Finlay Gillies, 17 George Hunter 18 Gordon Reid, 19 James Eddie, 20 Angus Macdonald, 21 Henry Pyrgos, 22 Ruaridh Jackson, 23 Sean Lamont.
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|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Glasgow vs Zebre|
|Sunday 20th April|
|Newport Gwent D'gons 10 - 20 Ospreys|
|Cardiff Blues 17 - 13 Scarlets|
|Saturday 19th April|
|Connacht 23 - 32 Munster|
|Zebre 26 - 13 Edinburgh|
|Friday 18th April|
|Glasgow 27 - 9 Ulster|
|Leinster 62 - 7 Benetton Treviso|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
Read the thoughts and opinions of Stuart Barnes with skysports.com