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Zebre will be without injured fly-half Luciano Orquera for Friday's PRO12 clash with reigning champions the Ospreys at Stadio XXV Aprile.
Orquera has a sprained ankle and is replaced by Alberto Chiesa in the number 10 jersey while Giovanbattista Venditti returns on the wing.
In the only other change to Christian Gajan's starting line-up, Emiliano Caffini is included ahead of Filippo Cristiano on the blindside.
There is a great deal of movement on the bench however as Carlo Festuccia, Salvatore Perugini, Flavio Tripodi, Filippo Ferrarini, Josh Sole, Alberto Benettin and Leonardo Sarto all make the squad.
Ospreys back rowers Justin Tipuric and Joe Bearman are injury concerns and will be monitored before the trip to Italy.
Prop Adam Jones is set to make his first start of the season after making his comeback from injury against Munster last weekend.
Zebre: 15 D Halangahu, 14 G Venditti, 13 M Pratichetti, 12 G Garcia (capt), 11 S Sinoti, 10 A Chiesa, 9 A Chillon, 8 Andries Van Schalkwyk, 7 M Bergamasco, 6 E Caffini, 5 M Van Vuren, 4 Q Geldenhuys, 3 L Redolfini, 2 Davide Giazzon, 1 Matias Aguero. Replacements: 16 C Festuccia, 17 S Perugini, 18 F Tripodi, 19 F Ferrarini, 20 J Sole, 21 L Martinelli, 22 A Benettin, 23 L Sarto.
Ospreys: 15 R Fussell, 14 H Dirksen, 13 A Beck, 12 A Bishop, 11 E Walker, 10 D Biggar, 9 K Fotuali'I, 1 R Bevington, 2 S Baldwin, 3 Adam Jones, 4 Alun Wyn Jones (Capt), 5 Ian Evans, 6 Ryan Jones, 7 Sam Lewis, 8 Jonathan Thomas, Replacements: 16 R Hibbard, 17 D Jones, 18 A Jarvis, 19 J Bearman, 20 G Stowers, 21 R Webb, 22 R Jones, 23 J Spratt
"I know they are bottom of the league but a couple of their games could have gone either way - the Glasgow game and certainly the defeat to Connacht," he said.
"We've gone out to Italy before and Italian sides have played particularly well against us. They are competitive, dangerous and I find them to be very inventive teams."
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|Friday 18th April|
|17:00||Leinster vs Benetton Treviso|
|19:35||Glasgow vs Ulster|
|Saturday 19th April|
|14:30||Zebre vs Edinburgh|
|18:15||Connacht vs Munster|
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Glasgow vs Zebre|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
|Ospreys 34 - 9 Cardiff Blues|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
|Saturday 1st March|
|Leinster 28 - 25 Glasgow|
|Scarlets 18 - 13 Munster|
|Connacht 38 - 6 Benetton Treviso|
|Zebre 15 - 10 Cardiff Blues|
Read the thoughts and opinions of Stuart Barnes with skysports.com