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Ospreys will be without Justin Tipuric for their trip to face RaboDirect PRO12 rivals Treviso.
The in-form flanker has been ruled out of the visitors' matchday squad, so Sam Lewis will instead start in the number seven jersey for Sunday's match.
Hooker Richard Hibbard is also not available as injury rules him out so Scott Baldwin gets a start in the front row.
Half-back pair Kahn Fotuali'i and Dan Biggar remain in tandem as the Ospreys look to finish their campaign on a high - their hopes of reaching the last eight of the Heineken Cup were dashed last week by a 15-all draw with Leicester.
Treviso are boosted for their final outing in Pool 2 by the return to fitness of Italian international Luke McLean.
He starts at full-back while Alberto Sgarbi also returns in the centres, replacing Andrea Pratichetti. Kristopher Burton and Edoardo Gori are back in the half-backs, taking over from Luca Morisi and Tobias Botes.
The hosts have lost all five of their European outings so far, picking up just a solitary losing bonus point. They were beaten 35-14 by table-topping Toulouse in wet conditions at Stade Ernest Wallon last time out.
Treviso: 15 Luke McLean, 14 Ludovico Nitoglia, 13 Tommaso Benvenuti, 12 Alberto Sgarbi, 11 Giiulio Toniolatti, 10 Kristopher Burton, 9 Edoardo Gori, 8 Robert Barbieri, 7 Alessandro Zanni, 6 Paul Derbyshire, 5 Francesco Minto, 4 Antonio Pavanello, 3 Lorenzo Cittadini, 2 Giovanni Maistri, 1 Michele Rizzo.
Replacements: 16 Enrico Ceccato, 17 Alberto de Marchi, 18 Ignacio Fernandez Rouyet, 19 Marco Fuser, 20 Valerio Bernabo, 21 Dean Budd, 22 Fabio Semenzato, 23 Andrea Pratichetti.
Ospreys: 15 Richard Fussell, 14 Thomas Grabham, 13 Tom Isaacs, 12 Andrew Bishop, 11 Eli Walker, 10 Dan Biggar, 9 Kahn Fotuali'i, 8 Joe Bearman, 7 Sam Lewis, 6 Jonathan Thomas, 5 James King, 4 Lloyd Peers, 3 Adam Jones, 2 Scott Baldwin, 1 Duncan Jones.
Replacements: 16 Matthew Dwyer, 17 Ryan Bevington, 18 Campbell Johnstone, 19 Ian Gough, 20 George Stowers, 21 Rhys Webb, 22 Matthew Morgan, 23 Jonathan Spratt.
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Read the thoughts and opinions of Stuart Barnes with skysports.com