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Connacht say goodbye to their number seven Johnny O'Connor when they take on Glasgow at the Galway Sportsground on Friday.
The 33-year-old flanker will turn out for the Irishmen for the 146th and last time before retiring from rugby after the game.
The Warriors have already qualified for the Play-Offs, but will probably need to win to give themselves any chance of gaining home advantage.
O'Connor represents the only personnel change to the forwards from the team who drew to Treviso last weekend. He is joined in the back-row by Andrew Browne and Eoin McKeon, who is at eight.
Eoin Griffin is named at outside centre for the last game of the season after his return from injury. This change sees the season's record try scorer, Danie Poolman, move on to the right wing.
On the bench, Adrian Flavin is named at replacement hooker and is in line to make his 142nd and final appearance for Connacht - his team for the last seven years as a win would help Connacht equal their best ever finish achieved last year.
Meanwhile, Glasgow could become the first Scottish side to secure a home play-off and Gregor Townsend has made nine personnel changes to the team that beat the Ospreys 35-17 at Scotstoun last month.
There are also two positional switches from the team that secured their play-off place against the defending champions, with only Sean Lamont, Pat MacArthur, Moray Low, Tim Swinson, Rob Harley and John Barclay remaining in the starting XV.
British and Irish Lions pair Stuart Hogg and Sean Maitland drop to the bench, along with Glasgow's player of the season Niko Matawalu, Ryan Grant and Josh Strauss. Alex Dunbar, Graeme Morrison, Duncan Weir and Al Kellock drop out of the squad altogether for the trip to Galway.
The Warriors are unbeaten in their last three contests with Connacht, whilst they have not been victorious at the Sportsground since April 2007.
Connacht: 15 Gavin Duffy (capt), 14 Danie Poolman, 13 Eoin Griffin, 12 Brian Murphy, 11 Fetu'u Vainikolo, 10 Dan Parks, 9 Kieran Marmion, 8 Eoin McKeon, 7 Johnny O'Connor, 6 Andrew Browne, 5 Mike McCarthy, 4 Michael Swift, 3 Ronan Loughney, 2 Ethienne Reynecke, 1 Brett Wilkinson.
Replacements (from): Adrian Flavin, Rodney Ah You, JP Cooney, Mick Kearney, John Muldoon, Mata Fifita, Paul O'Donohoe, Miah Nikora.
Glasgow: 15 Peter Murchie, 14 Tommy Seymour, 13 Sean Lamont, 12 Peter Horne, 11 DTH Van der Merwe, 10 Ruaridh Jackson, 9 Henry Pyrgos, 8 Ryan Wilson (c), 7 John Barclay, 6 Rob Harley, 5 Tom Ryder, 4 Tim Swinson, 3 Jon Welsh, 2 Pat MacArthur, 1 Moray Low.
Replacements: 16 Doug Hall, 17 Ryan Grant, 18 Ed Kalman, 19 James Eddie, 20 Josh Strauss, 21 Niko Matawalu, 22 Sean Maitland, 23 Stuart Hogg.
"We were delighted with our performance against the Ospreys which secured our play-off spot, but we know we'll face a big challenge tomorrow night at a ground we've not won at since 2007. Connacht are enjoying a great run of form at the moment, having lost just twice in their last seven games, so it will be an extremely tough game for us, but one we're all looking forward to."
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|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Glasgow vs Zebre|
|Sunday 20th April|
|Newport Gwent D'gons 10 - 20 Ospreys|
|Cardiff Blues 17 - 13 Scarlets|
|Saturday 19th April|
|Connacht 23 - 32 Munster|
|Zebre 26 - 13 Edinburgh|
|Friday 18th April|
|Glasgow 27 - 9 Ulster|
|Leinster 62 - 7 Benetton Treviso|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
Read the thoughts and opinions of Stuart Barnes with skysports.com