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The Lions host the Blues at Ellis Park on Saturday with both sides looking to get back to winning ways.
The Lions have already won twice so far this season but found the Sharks too good at Kings Park last time, while the Blues lost 38-22 at the Bulls.
Having faced local opposition in their first four Super Rugby outings, the pride of Johannesburg will finally take on an international opponent after missing out on the action during the 2013 season.
They will be up against a Blues outfit that will be desperate to return to Auckland with some points to show at the conclusion of their two-week tour, while the physical demands that the New Zealand sides present should give the Lions's coaching staff a better idea of just how well conditioned the group of fairly inexperienced players are.
The Lions have tweaked their backline with Marnitz Boshoff shifting from full-back to fly-half where he replaces Springbok Elton Jantjies.
Boshoff's accuracy with the boot was the key factor in his team's solid start to the season, but against the Blues his one-on-one defence is likely to be under the spotlight.
Having struggled with their set-pieces in recent times, the Blues are likely to rely on their enterprising backline players to pierce holes through what has been an impressive Lions defence.
To add to the potency they have at the back, former league player Benji Marshall will make his first start of the season, lining up at full-back in a Blues side featuring five changes to the one that lost to the Bulls last week.
Charles Piutau moves from full-back to wing to accommodate Marshall as youngster Tevita Li drops out of the side.
Pita Ahki is rewarded after scoring a try last week with a start at second five-eighths in place of Jackson Willison, who moves to the bench, while Chris Noakes replaces Simon Hickey at first five-eighths.
Lions: 15 Van Wyk, 14 Jonker, 13 Van Rensburg, 12 Watermeyer, 11 Skosan, 10 Boshoff, 9 De Klerk, 1 S van der Merwe, 2 Coetzee, 3 Redelinghuys, 4 Mostert, 5 F van der Merwe, 6 Kriel, 7 Britz, 8 Whiteley.
Replacements: 16 Wepener, 17 Fourie, 18 Dreyer, 19 Lusaseni, 20 Tecklenburg, 21 Cronje, 22 Jantjies, 23 Combrinck.
Blues: 15 Marshall, 14 Halai, 13 Moala, 12 Ahki, 11 Piutau, 10 Noakes, 9 Weepu , 1 Woodcock, 2 Parsons, 3 Faumuina, 4 Tuipulotu, 5 Donnelly, 6 O'Connor, 7 Braid, 8 Luatua.
Replacements: 16 McCartney, 17 Prattley, 18, Ta'avao, 19 Moli, 20 Manihera, 21 Hall, 22 Hickey, 23 Willison.
You can see all the action from Johannesburg as the Lions take on the Blues live on Sky Sports 2HD from 12.55pm on Saturday.
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|Friday 6th March|
|06:35||Chiefs vs Highlanders|
|08:40||Brumbies vs Western Force|
|Saturday 7th March|
|06:35||Blues vs Lions|
|08:40||Reds vs Waratahs|
|15:05||Cheetahs vs Bulls|
|17:10||Stormers vs Sharks|
|Friday 13th March|
|06:35||Hurricanes vs Blues|
|11:00||Western Force vs Melbourne Rebels|
|Saturday 14th March|
|03:30||Crusaders vs Lions|
|06:35||Highlanders vs Waratahs|
|08:40||Reds vs Brumbies|
|13:00||Stormers vs Chiefs|
|15:05||Cheetahs vs Sharks|
|Friday 20th March|
|06:35||Highlanders vs Hurricanes|
|08:40||Melbourne Rebels vs Lions|
|Saturday 21st March|
|06:35||Crusaders vs Cheetahs|
|15:05||Bulls vs Western Force|
|17:10||Sharks vs Chiefs|
|Sunday 22nd March|
|05:05||Waratahs vs Brumbies|
|Friday 27th March|
|06:35||Hurricanes vs Melbourne Rebels|
|09:00||Reds vs Lions|
|Saturday 28th March|
|05:30||Chiefs vs Cheetahs|
|06:35||Highlanders vs Stormers|
|08:40||Waratahs vs Blues|
|15:05||Sharks vs Western Force|
|Saturday 28th February|
|Lions 19 - 22 Stormers|
|Bulls 43 - 35 Sharks|
|Melbourne Rebels 15 - 20 Brumbies|
|Chiefs 40 - 16 Crusaders|
|Friday 27th February|
|Cheetahs 25 - 24 Blues|
|Western Force 13 - 42 Hurricanes|
|Highlanders 20 - 13 Reds|
|Saturday 21st February|
|Sharks 29 - 12 Lions|
|Stormers 27 - 16 Blues|
|Reds 18 - 6 Western Force|
|Highlanders 20 - 26 Crusaders|
|Friday 20th February|
|Bulls 13 - 17 Hurricanes|
|Melbourne Rebels 28 - 38 Waratahs|
|Chiefs 19 - 17 Brumbies|
|Sunday 15th February|
|Waratahs 13 - 25 Western Force|
|Saturday 14th February|
|Bulls 17 - 29 Stormers|
|Sharks 29 - 35 Cheetahs|
|Blues 18 - 23 Chiefs|
|Friday 13th February|
|Lions 8 - 22 Hurricanes|
|Brumbies 47 - 3 Reds|
|Crusaders 10 - 20 Melbourne Rebels|
Read the thoughts and opinions of Phil Edwards with skysports.com