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Darren Cave will start at inside centre for Ulster in the RaboDirect PRO12 clash against Ospreys at Ravenhill on Friday.
Cave played at No 12 for the Irish Wolfhounds in their recent victory over England Saxons and will be partnered in midfield by Jared Payne, who switches from full-back to outside centre as the sides return to RaboDirect Pro action for the first time since early January with third place in the table at stake.
In the back three, Ricky Andrew starts at full-back, Craig Gilroy, who also represented the Wolfhounds, is selected on the left wing and Michael Allen returns to the starting XV on the right.
With Paddy Jackson on international duty, James McKinney is named at fly-half where he will start alongside Ruan Pienaar, who is selected at scrum-half.
In the pack, Tom Court joins Rob Herring, and John Afoa in the front row, Johann Muller partners Lewis Stevenson in the second row and Robbie Diack, Sean Doyle and Roger Wilson form the back row.
Iain Henderson and Luke Marshall have been released by Ireland and are named on the bench. Ireland U20s full-back, Rory Scholes, is also named as a substitute and is in line to make his league debut if called upon.
Ospreys boss Steve Tandy has made changes to his side. In the back-line, there are four changes to the side that beat Sale in the LV= Cup last weekend.
Sam Davies, who played at fly-half against Sale, takes over from Richard Fussell at full-back while Jeff Hassler and Ashley Beck replace Tom Grabham and Matthew Jenkins at right wing and inside centre respectively. Matthew Morgan comes in for Davies at fly-half.
Among the forwards, there are five changes with Joe Bearman and Sam Lewis replacing Dan Baker and Lloyd Evans in the back-row.
The other changes sees Perry Parker making his first start at lock at Rhodri Hughes' expense, while Aaron Jarvis and Duncan Jones are the starting props in place of Dan Suter and Nicky Smith.
"These next four weeks are massive for us in terms of how the rest of the season plays out, and beyond that, in regards to what we are trying to build here for the longer term, whatever the future holds for the Ospreys," said Tandy.
"The last couple of weeks in the LV= Cup have been a valuable experience for us in terms of getting some meaningful game time for some of the next generation of Ospreys, and there is a lot to be pleased about.
"Ravenhill is always a very difficult place to go and play, whatever time of the season you go there, but even more so during the international period.
"They have a strong core that is available to them throughout the season, with some world class overseas players, and that allows them to stay strong during this period.
"It's an example of what can be achieved by union and club working together for the good of the game, certainly.
"We know that it's going to be a challenge for us but we are up for it and looking forward to getting this period of games started."
Ulster: 15 Andrew, 14 Gilroy, 13 Payne, 12 Cave, 11 Allen, 10 McKinney, 9 Pienaar; 1 Court, 2 Herring, 3 Afoa, 4 Muller (capt), 5 Stevenson, 6 Diack, 7 Doyle, 8 Wilson
Replacements: 16 Annett, 17 Black, 18 Lutton, 19 Henderson, 20 Williams, 21 P Marshall, 22 L Marshall, 23 Scholes
Ospreys: 15 Davies, 14 Hassler, 13 Spratt (capt), 12 Beck, 11 Natoga, 10 Morgan, 9 Habberfield; 1 Jones, 2 Baldwin, 3 Jarvis, 4 Peers, 5 Parker, 6 Ardron, 7 Lewis, 8 Bearman
Replacements: 16 Dwyer, 17 Bevington, 18 Suter, 19 Baker, 20 Allen, 21 Tebaldi, 22 Fussell, 23 Walker
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Glasgow vs Zebre|
|Saturday 19th April|
|Connacht 23 - 32 Munster|
|Zebre 26 - 13 Edinburgh|
|Friday 18th April|
|Glasgow 27 - 9 Ulster|
|Leinster 62 - 7 Benetton Treviso|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
|Ospreys 34 - 9 Cardiff Blues|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
Read the thoughts and opinions of Stuart Barnes with skysports.com