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Munster secured top spot in Heineken Cup Pool 6 with a battling 20-7 victory over Gloucester at Kingsholm.
The result leaves Munster six points clear of Edinburgh, who failed to get a winning bonus point against Perpignan at Murrayfield, meaning the Irish side are assured of a place in the quarter-finals.
Munster prevailed through tries in each half from wing Keith Earls and skipper Peter O'Mahony, while Ian Keatley kicked 10 points.
Gloucester, though, delivered a stirring display and they went down fighting, arguably deserving more than Charlie Sharples' converted try.
If Munster beat Thomond Park visitors Edinburgh in next weekend's final pool fixture, then it should be enough to secure a home tie as one of the top four group winners.
Gloucester skipper Billy Twelvetrees missed an 11th-minute penalty chance that would have opened the scoring, as Munster attempted to take the sting out of proceedings in front of a capacity 16,500 crowd.
Keatley showed him how it should be done when he bisected the Gloucester posts 10 minutes later, and Twelvetrees then drifted another penalty wide despite perfect conditions for goalkicking.
Twelvetrees was preferred as first-choice marksman to Freddie Burns, but he had done little to justify rugby director Nigel Davies' faith in him after Munster shaded a tense opening quarter.
Gloucester were noticeably improved on their performance against Saracens, but they had no answer when Munster increased the tempo eight minutes before half-time.
Superb approach work with ball in hand from lock Paul O'Connell and flanker Tommy O'Donnell spread panic in Gloucester's defence, which allowed Keatley space and time to kick into space and Earls finished clinically.
Keatley added the conversion, and for all Gloucester's determination and spirit, they found themselves in danger of facing a damage-limitation exercise before they responded magnificently just before half-time.
Wing Shane Monahan made initial inroads, and after lock Elliott Stooke powered onwards, scrum-half Dan Robson found flanker Matt Kvesic in support before Sharples finished majestically from 30 metres out, cutting back inside Johne Murphy and Keatley.
It was a superb riposte by Sharples after he failed to make either the elite England player squad or England Saxons group earlier this week, and Burns' conversion after he replaced Twelvetrees off the tee meant Munster's lead had been slashed by seven points.
Munster lock Dave Foley was fortunate to avoid a yellow card after he took out Stooke in the air as the second half got under way, but it did not knock Gloucester out of their stride as they enjoyed territorial supremacy.
Davies sent on back-row reinforcements after 50 minutes in the shape of England number eight Ben Morgan and Tonga flanker Sione Kalamafoni, and there remained an assuredness and dogged desire about Gloucester that had often been lacking on previous occasions this term.
Munster knew they were in a game far closer than many had predicted, and they had to call on all their European big-game experience to stay ahead of a Gloucester side that contested aggressively in every key area.
And it was a case of cometh the hour, cometh the men, as Munster scored a critical try midway through the second period that owed everything to their set-piece power.
Gloucester's scrum struggled to cope 15 metres out, and the outstanding O'Mahony crashed over from close range after scrum-half Conor Murray, who had been out injured for five weeks, marshalled his forwards superbly.
Keatley added the extras, and Gloucester found themselves 10 points behind approaching the final 15 minutes of an absorbing encounter, before another Keatley penalty finished them off and took Munster marching on.
Read the thoughts and opinions of Stuart Barnes with skysports.com