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London Irish handed Gloucester their first defeat of the Guinness Premiership season with a 15-10 triumph on Sunday.
League leaders Gloucester came into the match with a 100 percent record from their first five games, but came off second best in a defence-dominated contest at the Madejski Stadium.
The decisive moment occurred nine minutes from time when Exiles winger Tomas de Vedia crossed for his second try of the game.
London Irish debutant Peter Hewat - who arrived in the country from Australia on Tuesday - provided the the only points of the first-half with a fourth-minute penalty, although the former New South Wales full-back missed two other three-point chances.
The opening try did not arrive until the 43rd minute when de Vedia touched down for the hosts after collecting Shane Geraghty's cross-field kick.
That appeared to spark Gloucester into action and six minutes later Iain Balshaw collected his own chip ahead to cross the whitewash for the Cherry-and-Whites' first points.
Scotland international Chris Paterson, making his Gloucester debut on the wing, landed the conversion to reduce the deficit to 10-7.
However, the Exiles would not be denied and sealed the result in the 71st minute when de Vedia pounced on a grubber kick in the left corner after team-mate Topsy Ojo had failed to apply downward pressure.
The television match official - who had earlier denied Phil Murphy a try when the ball was grounded past the in-goal area - confirmed the score, although Delon Armitage was off-target with the conversion.
Paterson landed a penalty to reduce the deficit to 15-10 and set up an exciting final five minutes, but the hosts' defence stood firm to ensure the win.
Bath's victory at Newcastle earlier in the day means Gloucester's lead atop the Guinness Premiership is cut to just one point.
|Friday 20th December|
|20:00||Sale Sharks vs London Irish|
|Saturday 21st December|
|15:00||Exeter vs Newcastle|
|15:00||Bath vs Harlequins|
|15:00||Wasps vs Northampton|
|15:00||Saracens vs Leicester|
|Friday 27th December|
|TBC||Newcastle vs Wasps|
|Saturday 28th December|
|15:00||Northampton vs Bath|
|15:00||Worcester vs Saracens|
|15:00||Harlequins vs Exeter|
|15:00||Leicester vs Sale Sharks|
|Friday 3rd January|
|19:45||Newcastle vs Sale Sharks|
|Saturday 4th January|
|15:00||London Irish vs Worcester|
|15:00||Gloucester vs Saracens|
|15:00||Leicester vs Bath|
|Sunday 5th January|
|15:00||Wasps vs Exeter|
|Friday 7th February|
|19:45||Worcester vs Leicester|
|20:00||Sale Sharks vs Gloucester|
|Saturday 8th February|
|15:00||Harlequins vs Wasps|
|15:00||Bath vs Newcastle|
|15:00||Exeter vs Northampton|
|Sunday 9th February|
|15:00||Saracens vs London Irish|
|Friday 14th February|
|20:00||Sale Sharks vs Saracens|
|Saturday 15th February|
|15:00||Wasps vs London Irish|
|15:00||Northampton vs Worcester|
|15:00||Leicester vs Gloucester|
|Sunday 1st December|
|Newcastle 9 - 35 Harlequins|
|Saturday 30th November|
|Bath 21 - 16 Exeter|
|Worcester 10 - 33 Northampton|
|London Irish 12 - 19 Wasps|
|Saracens 24 - 19 Sale Sharks|
|Friday 29th November|
|Gloucester 17 - 22 Leicester|
|Sunday 24th November|
|Wasps 5 - 28 Bath|
|Saturday 23rd November|
|Northampton 18 - 0 Newcastle|
|Harlequins 27 - 19 Gloucester|
|Exeter 9 - 16 Saracens|
|Leicester 20 - 11 London Irish|
|Friday 22nd November|
|Sale Sharks 26 - 10 Worcester|
|Sunday 3rd November|
|Saracens 40 - 3 Newcastle|
|London Irish 14 - 19 Northampton|
|Saturday 2nd November|
|Leicester 16 - 23 Harlequins|
|Gloucester 30 - 32 Wasps|
|Friday 1st November|
|Sale Sharks 16 - 18 Exeter|
|Worcester 6 - 21 Bath|
|Sunday 27th October|
|Newcastle 13 - 11 London Irish|
|Wasps 22 - 12 Leicester|
|Saturday 26th October|
|Northampton 41 - 20 Saracens|
|Exeter 40 - 6 Worcester|
|Harlequins 24 - 3 Sale Sharks|
|Friday 25th October|
|Bath 15 - 13 Gloucester|
Read the thoughts and opinions of Stuart Barnes with skysports.com