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Tom Varndell's second-half try secured Leicester a 26-13 win away at Bristol.
The Tigers scored 16 unanswered points after the interval to ensure a perfect start to the defence of their Guinness Premiership title.
Despite missing 12 players away on World Cup duty, Leicester managed a repeat of their championship semi-final success when the sides last met in May.
Bristol commanded the early possession and territory, and fly-half David Hill made up for his earlier miss with a penalty kick on 11 minutes.
But that only served to spring the Tigers into life, as centre Sam Vesty and winger Ayoola Erinle combined for the game's first try.
Paul Burke added the conversion from in front of the sticks and Leicester had a 7-3 lead.
Full-back Josh Taumalolo broke down the right to lift Bristol hopes though, and winger Lee Robinson showed great strength to finish off the move after the ball had been moved into the middle.
Hill added the extras, but Burke quickly levelled the scores at 10-10 with a penalty from the right touchline.
Another Hill penalty on the stroke of half-time took Bristol into the interval 13-10 up.
Johnny Murphy took over the kicking duties from injured full-back Burke after the break and coolly slotted over his first points for the Tigers from a 45-metre penalty.
Vesty then kicked a drop goal from 35 metres out, as Leicester took the lead, and Burke ended his game with a pass to free Varndell down the left touchline.
The winger raced down the flank to take the game away from Bristol with Murphy kicking the conversion.
Murphy kicked a further penalty from out wide to stretch Leicester's lead, and seal victory for the champions.
Handling errors cost Bristol dear in the final minutes, and they will be keen to get England prospect Dan Ward-Smith back to full fitness as soon as possible.
|Friday 2nd May|
|19:45||Bath vs Northampton|
|Saturday 3rd May|
|15:00||Saracens vs Worcester|
|15:00||Wasps vs Newcastle|
|15:00||Gloucester vs London Irish|
|15:15||Sale vs Leicester|
|Sunday 4th May|
|14:00||Exeter vs Harlequins|
|Saturday 10th May|
|15:15||Newcastle vs Exeter|
|15:15||Northampton vs Wasps|
|15:15||Worcester vs Gloucester|
|15:15||Leicester vs Saracens|
|15:15||Harlequins vs Bath|
|15:15||London Irish vs Sale|
|Sunday 20th April|
|Newcastle 18 - 23 Saracens|
|Northampton 36 - 21 London Irish|
|Saturday 19th April|
|Wasps 38 - 30 Gloucester|
|Bath 32 - 20 Worcester|
|Exeter 12 - 55 Sale|
|Friday 18th April|
|Harlequins 24 - 20 Leicester|
|Sunday 13th April|
|London Irish 40 - 12 Newcastle|
|Saracens 28 - 24 Northampton|
|Saturday 12th April|
|Gloucester 17 - 18 Bath|
|Worcester 33 - 38 Exeter|
|Leicester 27 - 15 Wasps|
|Friday 11th April|
|Sale Sharks 12 - 27 Harlequins|
|Sunday 30th March|
|Newcastle 12 - 17 Worcester|
|Saturday 29th March|
|Northampton 16 - 22 Leicester|
|Wasps 20 - 32 Saracens|
|Exeter 13 - 14 Gloucester|
|Harlequins 23 - 9 London Irish|
|Friday 28th March|
|Bath 11 - 12 Sale Sharks|
|Sunday 23rd March|
|Leicester 45 - 15 Exeter|
|Saturday 22nd March|
|London Irish 23 - 44 Bath|
|Saracens 39 - 17 Harlequins|
|Gloucester 40 - 33 Newcastle|
|Sale Sharks 19 - 6 Northampton|
|Friday 21st March|
|Worcester 11 - 13 Wasps|
Read the thoughts and opinions of Stuart Barnes with skysports.com