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Fly-half Dan Biggar booted five penalties as the Ospreys remained in the Magners League title race with a 15-11 victory over Munster.
The Welshman produced a flawless place-kicking display as the Welsh outfit claimed their first ever win at Thomond Park.
The hard-fought victory puts Sean Holley's men on the brink of securing a home semi-final, while they trail leaders Leinster by just three points heading into the final game of the regular season.
Munster's stand-in captain Ronan O'Gara scored a try and kicked two penalties in reply, but he also missed four other kicks, totalling 11 points, as the Irish side's hopes of defending the league title took a serious hit.
The result leaves Munster in fourth place in the standings, meaning they will have to beat the Cardiff Blues away in two weeks' time and hope that other sides slip up in order to reach the semi-finals.
O'Gara opened the scoring 11 minutes into a scrappy affair at Thomond Park with a well-struck penalty.
The Ireland international missed two further penalty chances though, the second of which he really should have converted.
And his opposite number Biggar made him pay with clinical strikes after 23 and 31 minutes.
Prop Paul James foraged well at a ruck to tee up the young outside-half for a smashing strike from distance, and he punished Alan Quinlan with another well-struck effort on the half hour, setting up a 6-3 half-time lead.
Munster full-back Paul Warwick came closest to breaching the try-line but his sniping run on the left was ended by a knock on, forced by a Jerry Collins tackle.
The Ospreys seized the initiative at the start of the second half with a 42nd minute penalty from Biggar and Munster had to scramble back to deny Andrew Bishop a try after a Mike Phillips break.
Two more successful kicks from Biggar, the second coming after Munster number eight James Coughlan was sin-binned for hands in the ruck, left the home side with a mountain to climb at 15-3 down.
The home side fought hard in the final quarter and were rewarded on 71 minutes when O'Gara snuck down the blindside to touch down.
However, he could not add the conversion from wide out on the right and the Ospreys, with Tommy Bowe and Collins putting in some telling hits, deservedly held on to become the first Welsh region to win in Limerick since the Dragons did so six years ago.
|Friday 18th April|
|17:00||Leinster vs Benetton Treviso|
|19:35||Glasgow vs Ulster|
|Saturday 19th April|
|14:30||Zebre vs Edinburgh|
|18:15||Connacht vs Munster|
|Sunday 20th April|
|14:00||Cardiff Blues vs Scarlets|
|16:45||Newport Gwent D'gons vs Ospreys|
|Saturday 26th April|
|19:05||Glasgow vs Edinburgh|
|Thursday 1st May|
|17:00||Zebre vs Ospreys|
|Friday 2nd May|
|19:00||Benetton Treviso vs Glasgow|
|19:05||Scarlets vs Newport Gwent D'gons|
|19:30||Ulster vs Leinster|
|Saturday 3rd May|
|17:00||Edinburgh vs Munster|
|17:00||Connacht vs Cardiff Blues|
|Saturday 10th May|
|18:30||Leinster vs Edinburgh|
|18:30||Ospreys vs Connacht|
|18:30||Newport Gwent D'gons vs Benetton Treviso|
|18:30||Munster vs Ulster|
|18:30||Scarlets vs Cardiff Blues|
|18:30||Glasgow vs Zebre|
|Saturday 12th April|
|Munster 5 - 22 Glasgow|
|Scarlets 27 - 20 Zebre|
|Benetton Treviso 45 - 27 Newport Gwent D'gons|
|Friday 11th April|
|Edinburgh 22 - 29 Cardiff Blues|
|Ulster 58 - 12 Connacht|
|Ospreys 25 - 19 Leinster|
|Friday 4th April|
|Glasgow 29 - 10 Benetton Treviso|
|Thursday 3rd April|
|Newport Gwent D'gons 19 - 23 Edinburgh|
|Sunday 30th March|
|Scarlets 32 - 30 Connacht|
|Saturday 29th March|
|Leinster 22 - 18 Munster|
|Cardiff Blues 28 - 23 Ulster|
|Benetton Treviso 20 - 16 Edinburgh|
|Zebre 25 - 25 Newport Gwent D'gons|
|Friday 28th March|
|Glasgow 11 - 9 Ospreys|
|Sunday 23rd March|
|Newport Gwent D'gons 8 - 24 Connacht|
|Saturday 22nd March|
|Munster 14 - 3 Benetton Treviso|
|Glasgow 14 - 6 Scarlets|
|Friday 21st March|
|Edinburgh 3 - 9 Ulster|
|Leinster 27 - 0 Zebre|
|Ospreys 34 - 9 Cardiff Blues|
|Friday 14th March|
|Ulster 26 - 13 Scarlets|
|Saturday 1st March|
|Leinster 28 - 25 Glasgow|
|Scarlets 18 - 13 Munster|
|Connacht 38 - 6 Benetton Treviso|
|Zebre 15 - 10 Cardiff Blues|
Read the thoughts and opinions of Stuart Barnes with skysports.com