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Tom Homer kicked a penalty two minutes from time to give London Irish a controversial first Aviva Premiership win of the season.
Northampton were convinced that Jonathan Joseph knocked-on as he offunloaded to Homer just prior to the hosts being penalised.
The visitors had taken a seventh-minute lead when Homer kicked a 30-metre penalty after Tom Mercey was punished for hauling down Nick Kennedy at a line-out.
Within three minutes the Saints were level. A crunching tackle by Chris Hala'ufia on Paul Diggin was adjudged to be high by the touch judge and Ryan Lamb kicked the equalising penalty.
Irish should have restored their advantage but Homer's penalty attempt from 35 metres out rebounded back off a post.
Northampton scrum-half Martin Roberts made the first clean break of the game and his long pass found Noah Cato but the wing was easily hauled down.
Dan Bowden then split the home defence with an eye-catching run but Irish gave away a penalty just as they appeared likely to threaten the home line.
Northampton exerted pressure on the Irish eight at the set scrum but they could not make that pay in terms of points as both sides made frequent elementary errors.
Eventually two neat breaks from Roberts sparked the game into some life to enable the home side to build up some pressure in the opposition 22.
London Irish were penalised and Lamb knocked over a simple penalty, but with the last kick of the half the outside half missed with another straightforward attempt after Irish prop Leo Halavatau was sin-binned for dragging down a maul.
In Halavatau's 10-minute absence, Northampton never looked like extending their 6-3 interval advantage as Irish had the better of the opening exchanges of the second half.
The visitors then tied up the scores when Homer kicked a simple penalty after 51 minutes.
The first try went to the visitors when Hala'ufia produced a storming run to brush aside four home tacklers before offloading to Topsy Ojo. The wing was tackled just short of the line but the ball was moved along the line for Kennedy to outflank the cover and dive over in the corner.
Northampton immediately made two changes, bringing on Brian Mujati and Stephen Myler, with the latter having a quick chance to make an impact but he fired wide with a 40-metre penalty attempt.
With 10 minutes remaining the Saints twice opted not to kick penalties in favour of a kick to the corner and a forward drive, and it paid dividends when referee Martin Fox awarded a penalty try as Irish once again offended at the scrummage area.
Myler converted to put Northampton in front but there was still time for Homer's late penalty winner.
|Sunday 20th April|
|14:00||Northampton vs London Irish|
|15:00||Newcastle vs Saracens|
|Saturday 3rd May|
|15:00||Bath vs Northampton|
|15:00||Wasps vs Newcastle|
|15:00||Exeter vs Harlequins|
|15:00||Sale vs Leicester|
|15:00||Saracens vs Worcester|
|15:00||Gloucester vs London Irish|
|Saturday 10th May|
|15:15||Newcastle vs Exeter|
|15:15||Harlequins vs Bath|
|15:15||Leicester vs Saracens|
|15:15||Worcester vs Gloucester|
|15:15||Northampton vs Wasps|
|15:15||London Irish vs Sale|
|Saturday 19th April|
|Wasps 38 - 30 Gloucester|
|Bath 32 - 20 Worcester|
|Exeter 12 - 55 Sale|
|Friday 18th April|
|Harlequins 24 - 20 Leicester|
|Sunday 13th April|
|London Irish 40 - 12 Newcastle|
|Saracens 28 - 24 Northampton|
|Saturday 12th April|
|Gloucester 17 - 18 Bath|
|Worcester 33 - 38 Exeter|
|Leicester 27 - 15 Wasps|
|Friday 11th April|
|Sale Sharks 12 - 27 Harlequins|
|Sunday 30th March|
|Newcastle 12 - 17 Worcester|
|Saturday 29th March|
|Northampton 16 - 22 Leicester|
|Wasps 20 - 32 Saracens|
|Exeter 13 - 14 Gloucester|
|Harlequins 23 - 9 London Irish|
|Friday 28th March|
|Bath 11 - 12 Sale Sharks|
|Sunday 23rd March|
|Leicester 45 - 15 Exeter|
|Saturday 22nd March|
|London Irish 23 - 44 Bath|
|Saracens 39 - 17 Harlequins|
|Gloucester 40 - 33 Newcastle|
|Sale Sharks 19 - 6 Northampton|
|Friday 21st March|
|Worcester 11 - 13 Wasps|
|Sunday 2nd March|
|Newcastle 18 - 41 Leicester|
|Saturday 1st March|
|Northampton 39 - 13 Gloucester|
|Exeter 18 - 0 London Irish|
Read the thoughts and opinions of Stuart Barnes with skysports.com