Paulo Dybala and Gonzalo Higuain scored as Serie A leaders Juventus beat fourth-placed Lazio 2-0 on Sunday.
Radja Nainggolan stole the show as Roma secured a Coppa Italia quarter-final place with a 4-0 win over Sampdoria on Thursday.
Fiorentina put a dent in Juventus' title charge with a 2-1 win at the Stadio Artemio Franchi.
Lorenzo Tonelli marked his belated Napoli debut with a goal deep into stoppage time to secure a 2-1 win over 10-man Sampdoria.
Roma bounced back from their Serie A defeat to Juventus at the weekend by coming from behind to beat Chievo 3-1.
Joe Hart conceded five goals on Sunday afternoon as Torino lost 5-3 to Napoli in a thrilling Serie A encounter.
A rare goal from Kevin Strootman helped Roma reclaim second place in the Serie A table as they beat derby rivals Lazio 2-0 on Sunday.
Giovanni Simeone scored twice as Genoa inflicted a 3-1 defeat on reigning champions and Serie A leaders Juventus on Sunday.
Roma lost further ground on Serie A leaders Juventus when they were sunk by a late penalty and lost 2-1 at Atalanta.
Juventus maintained their four-point lead at the top of the Serie A table after Miralem Pjanic struck a late winner at Chievo.
Joe Hart was at fault for Mauro Icardi's first goal as Inter Milan beat Torino 2-1 in Serie A on Wednesday.
A brilliant strike by teenager Manuel Locatelli fired Milan to a hard-earned 1-0 win over Serie A leaders Juventus at San Siro.
Two goals from Paulo Dybala helped Juventus strengthen their lead at the top of Serie A with a 2-1 win over Udinese on Saturday.
Juventus moved for points clear at the top of Serie A after a 3-0 victory at Empoli, while Napoli slipped up at Atalanta.
Juventus, who beat Cagliari 4-0, move to the top of Serie A after Napoli were held to a 0-0 draw at Genoa.
Carlos Bacca responded to being dropped to the bench by firing AC Milan to a 1-0 Serie A victory over Sampdoria on Friday.
Mauro Icardi's stoppage-time strike earned Frank de Boer his first win as Inter Milan boss and sank Pescara 2-1.
Andrea Belotti scored a hat-trick and missed a penalty as Torino cruised to a 5-1 victory over Bologna in Serie A.
Inter Milan suffered a surprise 2-0 defeat to Chievo on the opening weekend of Serie A while Napoli also struggled.
Sampdoria have rescinded midfielder Nenad Krsticic's contract by mutual consent.