Crotone beat Lazio 3-1 on the final day to ensure survival, as Empoli went down after losing at already-relegated Palermo.
Napoli took advantage of Roma's derby defeat to close to within one point of second place in Serie A with victory over Inter Milan.
All the latest transfer rumours from the European papers, including reports Arsenal want Barcelona attacker Arda Turan.
Juventus took a giant leap towards securing an historic sixth consecutive Serie A title by thrashing hapless Genoa 4-0 in Turin.
Edin Dzeko set a new club record for Roma with both goals in a 2-0 victory over Empoli at the Stadio Olympico, as Lazio beat Sassuolo.
Chelsea loanee Juan Cuadrado was the hero for Juventus on a busy day of Serie A action, with Roma and Napoli also victorious.