Terry Butcher has confirmed Kris Commons and Kevin Thomson are unlikely to feature for Scotland this weekend.
Derby winger Commons is struggling with a hamstring problem, while Rangers midfielder Thomson suffered a slight knock during the Gers' 1-0 defeat to St Mirren on Sunday.
With George Burley's troops set to face Norway at Hampden Park on Saturday in the latest round of 2010 World Cup qualifiers, assistant boss Butcher admits Scotland are desperate to avoid further injuries before the crunch encounter.
"We have got Kevin Thomson and Kris Commons as well, who hasn't played for a couple of weeks with a hamstring problem and Kevin got a really sore one at St Mirren yesterday," he said.
"We'll see what the physios and doctors say tonight - that goes for all the other players as well because I'm sure there will be a few more knocks and niggles.
"But at the moment there's only a couple which could be a doubt, which is remarkable for Scotland because there's normally eight or nine, but hopefully it will just be those two cases.
"George is very philosophical about it, because he has to be, it's whoever turns up that we have to select from - simple as that. If players are struggling then we've got all this week to assess them and see where we are at the end of the week.
"We already have two players out, but the other players can more than make up for that."
Meanwhile, Butcher is hoping Scotland can put on a positive display in front of an expectant public this weekend.
"Everybody is excited and we have to make the players believe they can win the game and go out there and perform to the best of their abilities within the framework of the team," he said.
"It's about confidence. We are still at an early stage but the players have played a double-header (against Macedonia and Iceland), they know what it's all about, and hopefully after Saturday we will be in a good, strong position.
"It's up the staff and the players, in the few days that we have together, to make sure we are mentally right for the game and make sure we approach it properly.
"The players will be physically fit, that's not a problem.
"Mentally, it's about 'This is our kingdom, this is our place, and teams should come here and fear us' - hopefully they will do on Saturday."

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Bolton 0-2 Blackburn - Megson
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| Time | Fixture |
|---|---|
| Sunday 22nd November | |
| Barclays Premier League | |
| 13:30 | Bolton vs Blackburn |
| 15:00 | Tottenham vs Wigan |
| 16:00 | Stoke vs Portsmouth |
| Wednesday 25th November | |
| Barclays Premier League | |
| 19:45 | Hull vs Everton |
| 20:00 | Fulham vs Blackburn |
| Saturday 28th November | |
| Barclays Premier League | |
| 15:00 | Blackburn vs Stoke |
| 15:00 | Fulham vs Bolton |
| 15:00 | Man City vs Hull |
| 15:00 | Portsmouth vs Man Utd |
| 15:00 | West Ham vs Burnley |
| 15:00 | Wigan vs Sunderland |
| 17:30 | Aston Villa vs Tottenham |
| Sunday 29th November | |
| Barclays Premier League | |
| 12:00 | Wolverhampton vs Birmingham |
| 13:30 | Everton vs Liverpool |
| 16:00 | Arsenal vs Chelsea |
| Saturday 5th December | |
| Barclays Premier League | |
| 12:45 | Portsmouth vs Burnley |
| 15:00 | Arsenal vs Stoke |
| 15:00 | Aston Villa vs Hull |
| 15:00 | Blackburn vs Liverpool |
| 15:00 | West Ham vs Man Utd |
| Time | Result |
|---|---|
| Saturday 21st November | |
| Barclays Premier League | |
| Liverpool 2 - 2 Man City | |
| Hull 3 - 3 West Ham | |
| Chelsea 4 - 0 Wolverhampton | |
| Sunderland 1 - 0 Arsenal | |
| Man Utd 3 - 0 Everton | |
| Birmingham 1 - 0 Fulham | |
| Burnley 1 - 1 Aston Villa | |
| Monday 9th November | |
| Barclays Premier League | |
| Liverpool 2 - 2 Birmingham | |
| Sunday 8th November | |
| Barclays Premier League | |
| Hull 2 - 1 Stoke | |
| Wigan 1 - 1 Fulham | |
| Chelsea 1 - 0 Man Utd | |
| West Ham 1 - 2 Everton | |
| Saturday 7th November | |
| Barclays Premier League | |
| Aston Villa 5 - 1 Bolton | |
| Blackburn 3 - 1 Portsmouth | |
| Tottenham 2 - 0 Sunderland | |
| Wolverhampton 1 - 4 Arsenal | |
| Man City 3 - 3 Burnley | |
| Wednesday 4th November | |
| Barclays Premier League | |
| West Ham 2 - 1 Aston Villa | |
| Sunday 1st November | |
| Barclays Premier League | |
| Birmingham 0 - 0 Man City | |
| Saturday 31st October | |
| Barclays Premier League | |
| Arsenal 3 - 0 Tottenham | |
Skysports.com looks at the best and worst moments from the latest round of top-flight fixtures.
Pictures from Saturday's action where Liverpool draw with Man City and Arsenal lose away.
Take a look back at what Liverpool and Man City fans had to say following a 2-2 draw at Anfield.
Jermain Defoe helped himself to five goals as Tottenham demolished Wigan 9-1 at White Hart Lane to move into fourth spot in the table.
Follow all the action from Sunday's packed programme with the skysports.com Score Centre.
Bolton squandered the chance to climb out of the bottom three as they were beaten 2-0 at home by Blackburn.
Stoke collected all three points against Portsmouth thanks to a late strike from Ricardo Fuller.
Tony Pulis put Stoke's poor first-half performance against Portsmouth at the Britannia Stadium down to nerves.