Middlesbrough manager Gareth Southgate has confirmed that Robert Huth has suffered a fresh ankle injury.
Huth has suffered an injury-plagued time on Teesside since his £6million move from Chelsea in 2006.
The Germany international has been limited to just 23 league starts, but he looked to have put his problems behind him this season after starting the first six games with no problems.
But now Huth has damaged ankle ligaments, which will be a huge concern for Boro given he had to undergo ankle surgery last year.
"Robert has a problem with his ankle ligaments but we don't yet know the full extent of the injury," said Southgate.
"The area is very swollen and it's difficult to give an accurate assessment at this stage.
"However we should have a clearer picture by the end of the week."
With Emanuel Pogatetz suspended and youngster Rhys Williams already sidelined, Boro are left with few options other than Chris Riggott and David Wheater in central defence.
Jonathan Grounds, who was recalled from a loan spell at Norwich, can also play in the middle, but with Andrew Taylor also set for a time on the sidelines with a hip injury, he is needed at left-back.
Southgate is now keeping his fingers crossed that his international players return unscathed - last time round both Tuncay Sanli and Mohamed Shawky picked up injuries with their countries.
He added: "The international break wasn't too kind to us last time.
"We've got a lot of players away again this week. In fact we've got only six or seven left.
"Hopefully everybody will come back fine this time. After the win against Wigan, everybody will want to play against Chelsea."
Southgate confirmed that Tuncay could be back for the next Premier League clash with Luiz Felipe Scolari's leaders after his knee problem.
"The Chelsea game is one of Tuncay's targets but he will not be considered unless he is fully fit," he said.
"I can't say yet when he will be ready to start, but he should be very close by the end of next week. The week after is a more realistic target but we'll have to see."
| Time | Fixture |
|---|---|
| Sunday 8th November | |
| Barclays Premier League | |
| 16:00 | Chelsea vs Man Utd |
| Monday 9th November | |
| Barclays Premier League | |
| 20:00 | Liverpool vs Birmingham |
| Saturday 21st November | |
| Barclays Premier League | |
| 12:45 | Liverpool vs Man City |
| 15:00 | Birmingham vs Fulham |
| 15:00 | Burnley vs Aston Villa |
| 15:00 | Chelsea vs Wolverhampton |
| 15:00 | Hull vs West Ham |
| 15:00 | Sunderland vs Arsenal |
| 17:30 | Man Utd vs Everton |
| Sunday 22nd November | |
| Barclays Premier League | |
| 13:30 | Bolton vs Blackburn |
| 15:00 | Tottenham vs Wigan |
| 16:00 | Stoke vs Portsmouth |
| Wednesday 25th November | |
| Barclays Premier League | |
| 19:45 | Hull vs Everton |
| 20:00 | Fulham vs Blackburn |
| Saturday 28th November | |
| Barclays Premier League | |
| 15:00 | Blackburn vs Stoke |
| 15:00 | Fulham vs Bolton |
| 15:00 | Man City vs Hull |
| 15:00 | Portsmouth vs Man Utd |
| 15:00 | West Ham vs Burnley |
| 15:00 | Wigan vs Sunderland |
| Time | Result |
|---|---|
| Sunday 8th November | |
| Barclays Premier League | |
| West Ham 1 - 2 Everton | |
| Wigan 1 - 1 Fulham | |
| Hull 2 - 1 Stoke | |
| Saturday 7th November | |
| Barclays Premier League | |
| Wolverhampton 1 - 4 Arsenal | |
| Man City 3 - 3 Burnley | |
| Tottenham 2 - 0 Sunderland | |
| Blackburn 3 - 1 Portsmouth | |
| Aston Villa 5 - 1 Bolton | |
| Wednesday 4th November | |
| Barclays Premier League | |
| West Ham 2 - 1 Aston Villa | |
| Sunday 1st November | |
| Barclays Premier League | |
| Birmingham 0 - 0 Man City | |
| Saturday 31st October | |
| Barclays Premier League | |
| Man Utd 2 - 0 Blackburn | |
| Sunderland 2 - 2 West Ham | |
| Portsmouth 4 - 0 Wigan | |
| Bolton 0 - 4 Chelsea | |
| Stoke 2 - 2 Wolverhampton | |
| Fulham 3 - 1 Liverpool | |
| Burnley 2 - 0 Hull | |
| Everton 1 - 1 Aston Villa | |
| Arsenal 3 - 0 Tottenham | |
| Sunday 25th October | |
| Barclays Premier League | |
| West Ham 2 - 2 Arsenal | |
| Pos | Team | P | Pts |
|---|---|---|---|
| 1 | Chelsea | 11 | 27 |
| 2 | Arsenal | 11 | 25 |
| 3 | Manchester United | 11 | 25 |
| 4 | Tottenham Hotspur | 12 | 22 |
| 5 | Aston Villa | 12 | 21 |
| 6 | Manchester City | 11 | 20 |
| 7 | Liverpool | 11 | 18 |
| 8 | Sunderland | 12 | 17 |
| 9 | Stoke City | 11 | 16 |
| 10 | Burnley | 12 | 16 |
| 11 | Fulham | 10 | 14 |
| 12 | Wigan Athletic | 11 | 13 |
| 13 | Blackburn Rovers | 11 | 13 |
| 14 | Everton | 10 | 12 |
| 15 | Birmingham City | 11 | 11 |
| 16 | Bolton Wanderers | 11 | 11 |
| 17 | West Ham United | 11 | 10 |
| 18 | Wolverhampton Wanderers | 12 | 10 |
| 19 | Hull City | 11 | 8 |
| 20 | Portsmouth | 12 | 7 |
Sunderland fan Lucinda Gittins was strutting her stuff in the Soccer AM studios this week.
With Didier Drogba in frightening form, Paul Merson expects Chelsea to beat Man Utd on Sunday.
Hull came from behind to beat Stoke 2-1 at the KC Stadium to ease the pressure on Phil Brown.
Patrice Evra has admitted that he wants to beat Chelsea more than any other team in the Premier League.
Fulham stayed strong and held firm at Wigan to keep the Latics at bay and come away with a hard-earned point.
Birmingham's Scott Dann believes Liverpool will be a tough nut to crack despite their dip in form.
Everton claimed their first league win in five attempts with a hard-fought 2-1 success at West Ham.