Van Persie celebrates
Arsenal are back in the title race after a stunning win at leaders Chelsea as Wayne Rooney's 100th career goal settled the Manchester derby.
Tony Adams enjoyed his first home win as Portsmouth manager, while David Moyes celebrated his 300th game as Everton boss with a narrow victory at Tottenham.
Robin van Persie struck twice in the second half as Arsenal came from behind to win 2-1 at Chelsea, whose stuttering form at Stamford Bridge continues.
Despite a nervy opening, Arsenal could have snatched the lead, but former Chelsea defender William Gallas was unable to reach the loose ball after Petr Cech had parried.
Chelsea took the lead in fortunate circumstances on 31 minutes when Jose Bosingwa's low cross was turned past his own keeper by Johan Djourou.
The leaders failed to build on their advantage and were punished for their failure to test Manuel Almunia when Van Persie scored twice inside three second-half minutes.
There was an element of controversy about the equaliser on 59 minutes when Denilson played the ball through to Van Persie, who looked two yards offside.
The Dutch striker did not flinch, however, and smacked an unstoppable right-foot shot into the top corner.
And three minutes later, Van Persie swivelled to send a low left-footed attempt beyond Cech after Emmanuel Adebayor had knocked down a free-kick to leave Arsenal seven points behind their London rivals.
Manchester United showed how far local rivals City still have to go to become a major force after the champions won 1-0 in the 150th derby.
The reigning champions dominated the first half at the City of Manchester Stadium as Mark Hughes' men put in a surprisingly lacklustre shift.
Yet, for all City being off the pace, they could have nicked an opening goal when Stephen Ireland's shot - after a poor punch by Edwin van der Sar - clipped the outside of the post.
United grabbed the decisive goal three minutes before half-time when Michael Carrick's shot was pushed out by Joe Hart to provide Rooney with a simple tap-in.
City emerged a more determined side in the second half and were given a helping hand on 68 minutes when Cristiano Ronaldo picked up his second yellow card after inexplicably raising his hands to stop Rooney's corner.
Ronaldo, who had been cautioned moments earlier for a foul on Shaun Wright-Phillips, claimed to have heard a whistle, but referee Howard Webb was non-plussed.
In injury-time, Patrice Evra cleared Richard Dunne's effort off the line before Rooney's ambitious long-range attempt was pushed away by the retreating Hart.
Harry Redknapp suffered his first home defeat as Spurs boss as Steven Pienaar's goal earned Everton a 1-0 win at White Hart Lane.
Everton's away-day joy was marred by an early injury to Yakubu, with the Nigerian striker to miss the rest of the season with a ruptured Achilles tendon.
The only goal arrived six minutes into the second half after Pienaar received a quickly-taken free-kick and his shot took a wicked deflection to fizz beyond a helpless Heurelho Gomes.
Portsmouth provided Adams with his first three points at Fratton Park after a thrilling 3-2 victory over struggling Blackburn.
All the action came in the second half as Pompey took the lead on 49 minutes when Glen Johnson's cross was headed home by Peter Crouch.
Pompey increased their lead just four minutes later when Niko Kranjcar released Jermain Defoe and the fit-again striker drilled a low shot past Paul Robinson.
But Blackburn rallied and pulled a goal back on 62 minutes when substitute Matt Derbyshire made an immediate impact as his header looped over David James.
And just five minutes later, Rovers were level as Tugay strode forward and drove a low shot beyond James and inside the post from 25 yards.
Rovers could not hold on, however, as Pompey snatched a winner on 79 minutes after Papa Bouba Diop's shot was saved and the ball eventually broke for Sean Davis to lift over Robinson.

Stoke 1-0 Portsmouth - Fuller and Sorensen
Tottenham 9-1 Wigan - Defoe
Stoke 1-0 Portsmouth - Pulis
Stoke 1-0 Portsmouth - Shreeves' blog
Stoke 1-0 Portsmouth - Hart
Tottenham 9-1 Wigan - Redknapp
Tottenham 9-1 Wigan - Martinez
Bolton 0-2 Blackburn - Megson
| Time | Fixture |
|---|---|
| Wednesday 25th November | |
| Barclays Premier League | |
| 19:45 | Hull vs Everton |
| 20:00 | Fulham vs Blackburn |
| Saturday 28th November | |
| Barclays Premier League | |
| 15:00 | Blackburn vs Stoke |
| 15:00 | Fulham vs Bolton |
| 15:00 | Man City vs Hull |
| 15:00 | Portsmouth vs Man Utd |
| 15:00 | West Ham vs Burnley |
| 15:00 | Wigan vs Sunderland |
| 17:30 | Aston Villa vs Tottenham |
| Sunday 29th November | |
| Barclays Premier League | |
| 12:00 | Wolverhampton vs Birmingham |
| 13:30 | Everton vs Liverpool |
| 16:00 | Arsenal vs Chelsea |
| Saturday 5th December | |
| Barclays Premier League | |
| 12:45 | Portsmouth vs Burnley |
| 15:00 | Arsenal vs Stoke |
| 15:00 | Aston Villa vs Hull |
| 15:00 | Blackburn vs Liverpool |
| 15:00 | West Ham vs Man Utd |
| 15:00 | Wigan vs Birmingham |
| 15:00 | Wolverhampton vs Bolton |
| 17:30 | Man City vs Chelsea |
| Time | Result |
|---|---|
| Sunday 22nd November | |
| Barclays Premier League | |
| Bolton 0 - 2 Blackburn | |
| Tottenham 9 - 1 Wigan | |
| Stoke 1 - 0 Portsmouth | |
| Saturday 21st November | |
| Barclays Premier League | |
| Liverpool 2 - 2 Man City | |
| Hull 3 - 3 West Ham | |
| Sunderland 1 - 0 Arsenal | |
| Chelsea 4 - 0 Wolverhampton | |
| Man Utd 3 - 0 Everton | |
| Birmingham 1 - 0 Fulham | |
| Burnley 1 - 1 Aston Villa | |
| Monday 9th November | |
| Barclays Premier League | |
| Liverpool 2 - 2 Birmingham | |
| Sunday 8th November | |
| Barclays Premier League | |
| Hull 2 - 1 Stoke | |
| Wigan 1 - 1 Fulham | |
| Chelsea 1 - 0 Man Utd | |
| West Ham 1 - 2 Everton | |
| Saturday 7th November | |
| Barclays Premier League | |
| Aston Villa 5 - 1 Bolton | |
| Blackburn 3 - 1 Portsmouth | |
| Tottenham 2 - 0 Sunderland | |
| Wolverhampton 1 - 4 Arsenal | |
| Man City 3 - 3 Burnley | |
| Pos | Team | P | Pts |
|---|---|---|---|
| 1 | Chelsea | 13 | 33 |
| 2 | Manchester United | 13 | 28 |
| 3 | Arsenal | 12 | 25 |
| 4 | Tottenham Hotspur | 13 | 25 |
| 5 | Aston Villa | 13 | 22 |
| 6 | Manchester City | 12 | 21 |
| 7 | Liverpool | 13 | 20 |
| 8 | Sunderland | 13 | 20 |
| 9 | Stoke City | 13 | 19 |
| 10 | Burnley | 13 | 17 |
| 11 | Blackburn Rovers | 12 | 16 |
| 12 | Fulham | 12 | 15 |
| 13 | Birmingham City | 13 | 15 |
| 14 | Everton | 12 | 15 |
| 15 | Wigan Athletic | 13 | 14 |
| 16 | Hull City | 13 | 12 |
| 17 | West Ham United | 13 | 11 |
| 18 | Bolton Wanderers | 12 | 11 |
| 19 | Wolverhampton Wanderers | 13 | 10 |
| 20 | Portsmouth | 13 | 7 |
Skysports.com looks at the best and worst moments from the latest round of top-flight fixtures.
Take a look back at what Liverpool and Man City fans had to say following a 2-2 draw at Anfield.
Bristol City fan Hannah Shine was strutting her as the Soccerette in the Soccer AM studios this week.
Arsenal boss Arsene Wenger accused his players of choking after watching Sunderland shatter their unbeaten record.
Steven Gerrard is confident Liverpool can 'put things right' and insists morale remains positive despite the team's flagging season.
Darren Bent admits he could have crumbled under the criticism he received after England's game against Brazil.
John Obi Mikel is confident team-mate Gael Kakuta can handle the controversy surrounding his early career.
Manchester United captain Gary Neville admits it is a 'pet hate' that players are too dependent on agents.