Bournemouth knocked out Johnstone's Paint Trophy holders Milton Keynes Dons, while Shrewsbury Town cruised through to the next round.
Darren Anderton was the hero for Bournemouth as he struck the only goal of the game at stadium:mk to dump out reigning champions MK Dons, who also had Flavien Belson dismissed.
Paul Simpson's Shrewsbury stormed to a remarkable 7-0 triumph at Wycombe Wanderers, with Grant Holt netting five in the rout.
League Two outfit Dagenham & Redbridge were victorious in their clash with Darren Ferguson's Peterborough.
Mark Nwokeji grabbed the only goal of the fixture at London Road in the 65th minute to ensure the Daggers are in the draw for the area quarter-finals.
Walsall came from a goal down in their encounter against Cheltenham Town at Whaddon Road with Michael Ricketts grabbing the winner with 16 minutes remaining.
Brighton & Hove Albion progressed in their match versus Leyton Orient, claiming a 5-4 penalty win after the 90 minutes had ended 2-2.
Luton Town also claimed shoot-out glory as they won 4-3 on penalties against Brentford after the contest had finished 2-2 after normal time.
Colchester United secured a 1-0 win over Gillingham at Priestfield courtesy of Mark Yeates' goal on the hour mark.
Swindon Town are through to the next round after they disposed of Hereford United with Lee Peacock netting the decisive goal on 84 minutes.

League One Round Up - 21st November
Yeovil 1-1 Charlton - Highlights
Bristol Rovers 2-1 Gillingham - Highlights
Millwall 0-2 Wycombe - Highlights
Brentford 1-1 Walsall - Highlights
Carlisle 0-1 Swindon - Highlights
Oldham 2-2 Colchester - Highlights
Huddersfield 2-1 Hartlepool - Highlights
| Time | Fixture |
|---|---|
| Tuesday 24th November | |
| Coca-Cola Football League One | |
| 19:45 | Charlton vs Bristol Rovers |
| 19:45 | Colchester vs Stockport |
| 19:45 | Exeter vs Millwall |
| 19:45 | Gillingham vs Yeovil |
| 19:45 | Hartlepool vs Southampton |
| 19:45 | Leeds vs Leyton Orient |
| 19:45 | Milton Keynes Dons vs Carlisle |
| 19:45 | Norwich vs Brighton |
| 19:45 | Swindon vs Huddersfield |
| 19:45 | Tranmere vs Southend |
| 19:45 | Walsall vs Oldham |
| 19:45 | Wycombe vs Brentford |
| Tuesday 1st December | |
| Coca-Cola Football League One | |
| 19:45 | Brentford vs Colchester |
| 19:45 | Brighton vs Charlton |
| 19:45 | Bristol Rovers vs Exeter |
| 19:45 | Carlisle vs Hartlepool |
| 19:45 | Huddersfield vs Tranmere |
| 19:45 | Leyton Orient vs Gillingham |
| 19:45 | Millwall vs Milton Keynes Dons |
| 19:45 | Oldham vs Leeds |
| Time | Result |
|---|---|
| Saturday 21st November | |
| Coca-Cola Football League One | |
| Bristol Rovers 2 - 1 Gillingham | |
| Brighton 0 - 3 Leeds | |
| Yeovil 1 - 1 Charlton | |
| Oldham 2 - 2 Colchester | |
| Carlisle 0 - 1 Swindon | |
| Brentford 1 - 1 Walsall | |
| Stockport 1 - 3 Exeter | |
| Southampton 2 - 2 Norwich | |
| Leyton Orient 2 - 1 Tranmere | |
| Millwall 0 - 2 Wycombe | |
| Huddersfield 2 - 1 Hartlepool | |
| Friday 20th November | |
| Coca-Cola Football League One | |
| Southend 2 - 1 Milton Keynes Dons | |
| Sunday 15th November | |
| Coca-Cola Football League One | |
| Southampton 1 - 3 Brighton | |
| Saturday 14th November | |
| Coca-Cola Football League One | |
| Huddersfield 6 - 0 Wycombe | |
| Bristol Rovers 3 - 2 Carlisle | |
| Yeovil 1 - 0 Southend | |
| Charlton 5 - 1 Milton Keynes Dons | |
| Walsall 2 - 0 Stockport | |
| Brentford 2 - 2 Millwall | |
| Hartlepool 1 - 0 Leyton Orient | |
| Pos | Team | P | Pts |
|---|---|---|---|
| 1 | Leeds United | 16 | 39 |
| 2 | Charlton Athletic | 17 | 33 |
| 3 | Huddersfield Town | 17 | 30 |
| 4 | Colchester United | 17 | 30 |
| 5 | Norwich City | 17 | 29 |
| 6 | Milton Keynes Dons | 17 | 29 |
| 7 | Bristol Rovers | 17 | 28 |
| 8 | Millwall | 17 | 25 |
| 9 | Swindon Town | 16 | 25 |
| 10 | Walsall | 17 | 24 |
| 11 | Southend United | 17 | 23 |
| 12 | Hartlepool United | 17 | 23 |
| 13 | Yeovil Town | 17 | 22 |
| 14 | Oldham Athletic | 17 | 21 |
| 15 | Exeter City | 17 | 21 |
| 16 | Brentford | 17 | 19 |
| 17 | Leyton Orient | 17 | 19 |
| 18 | Gillingham | 17 | 18 |
| 19 | Carlisle United | 17 | 17 |
| 20 | Brighton and Hove Albion | 17 | 17 |
| 21 | Stockport County | 17 | 14 |
| 22 | Southampton | 17 | 13 |
| 23 | Wycombe Wanderers | 17 | 11 |
| 24 | Tranmere Rovers | 17 | 10 |
Bristol City fan Hannah Shine was strutting her as the Soccerette in the Soccer AM studios this week.
Peter Beagrie wonders if Roy Keane and Ipswich Town were ever really suited to each other.
Jon-Paul Pittman tells Chris Burton about his return to the big time and Wycombe's current plight.
Leeds extended their lead at the top of League One with a 3-0 win over Brighton at the Withdean Stadium.
Leeds eased to a 3-0 victory over Brighton as the Seagulls went down to defeat for the first time under Gus Poyet.
Super-sub Stephen Hughes' equaliser earned Norwich a battling 2-2 draw against Southampton.
Wycombe earned their first away win of the season at Millwall to climb off the foot of League One.
Charlie Austin needed just three minutes of his full debut to secure a 1-0 win for Swindon over Carlisle.