Bournemouth knocked out Johnstone's Paint Trophy holders Milton Keynes Dons, while Shrewsbury Town cruised through to the next round.
Darren Anderton was the hero for Bournemouth as he struck the only goal of the game at stadium:mk to dump out reigning champions MK Dons, who also had Flavien Belson dismissed.
Paul Simpson's Shrewsbury stormed to a remarkable 7-0 triumph at Wycombe Wanderers, with Grant Holt netting five in the rout.
League Two outfit Dagenham & Redbridge were victorious in their clash with Darren Ferguson's Peterborough.
Mark Nwokeji grabbed the only goal of the fixture at London Road in the 65th minute to ensure the Daggers are in the draw for the area quarter-finals.
Walsall came from a goal down in their encounter against Cheltenham Town at Whaddon Road with Michael Ricketts grabbing the winner with 16 minutes remaining.
Brighton & Hove Albion progressed in their match versus Leyton Orient, claiming a 5-4 penalty win after the 90 minutes had ended 2-2.
Luton Town also claimed shoot-out glory as they won 4-3 on penalties against Brentford after the contest had finished 2-2 after normal time.
Colchester United secured a 1-0 win over Gillingham at Priestfield courtesy of Mark Yeates' goal on the hour mark.
Swindon Town are through to the next round after they disposed of Hereford United with Lee Peacock netting the decisive goal on 84 minutes.

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| Time | Fixture |
|---|---|
| Saturday 14th November | |
| Coca-Cola Football League One | |
| 12:05 | Huddersfield vs Wycombe |
| 15:00 | Brentford vs Millwall |
| 15:00 | Bristol Rovers vs Carlisle |
| 15:00 | Charlton vs Milton Keynes Dons |
| 15:00 | Colchester vs Exeter |
| 15:00 | Gillingham vs Oldham |
| 15:00 | Hartlepool vs Leyton Orient |
| 15:00 | Norwich vs Tranmere |
| 15:00 | Walsall vs Stockport |
| 15:00 | Yeovil vs Southend |
| Sunday 15th November | |
| Coca-Cola Football League One | |
| 16:30 | Southampton vs Brighton |
| Friday 20th November | |
| Coca-Cola Football League One | |
| 19:45 | Southend vs Milton Keynes Dons |
| Saturday 21st November | |
| Coca-Cola Football League One | |
| 15:00 | Brentford vs Walsall |
| 15:00 | Brighton vs Leeds |
| 15:00 | Bristol Rovers vs Gillingham |
| 15:00 | Carlisle vs Swindon |
| 15:00 | Huddersfield vs Hartlepool |
| 15:00 | Leyton Orient vs Tranmere |
| 15:00 | Millwall vs Wycombe |
| 15:00 | Oldham vs Colchester |
| Time | Result |
|---|---|
| Sunday 1st November | |
| Coca-Cola Football League One | |
| Oldham 0 - 1 Huddersfield | |
| Saturday 31st October | |
| Coca-Cola Football League One | |
| Stockport 1 - 3 Norwich | |
| Leeds 4 - 0 Yeovil | |
| Leyton Orient 2 - 2 Southampton | |
| Exeter 3 - 0 Brentford | |
| Tranmere 1 - 4 Swindon | |
| Millwall 2 - 1 Colchester | |
| Milton Keynes Dons 2 - 1 Bristol Rovers | |
| Wycombe 2 - 3 Walsall | |
| Brighton 3 - 3 Hartlepool | |
| Carlisle 3 - 1 Charlton | |
| Friday 30th October | |
| Coca-Cola Football League One | |
| Southend 1 - 0 Gillingham | |
| Tuesday 27th October | |
| Coca-Cola Football League One | |
| Bristol Rovers 0 - 4 Leeds | |
| Saturday 24th October | |
| Coca-Cola Football League One | |
| Norwich 1 - 0 Swindon | |
| Hartlepool 1 - 0 Tranmere | |
| Bristol Rovers 1 - 2 Yeovil | |
| Colchester 2 - 1 Walsall | |
| Exeter 1 - 1 Wycombe | |
| Brentford 2 - 0 Stockport | |
| Southampton 3 - 1 Milton Keynes Dons | |
| Pos | Team | P | Pts |
|---|---|---|---|
| 1 | Leeds United | 15 | 36 |
| 2 | Charlton Athletic | 15 | 29 |
| 3 | Milton Keynes Dons | 15 | 29 |
| 4 | Colchester United | 15 | 28 |
| 5 | Norwich City | 15 | 25 |
| 6 | Huddersfield Town | 15 | 24 |
| 7 | Millwall | 15 | 24 |
| 8 | Swindon Town | 15 | 22 |
| 9 | Bristol Rovers | 15 | 22 |
| 10 | Southend United | 15 | 20 |
| 11 | Hartlepool United | 15 | 20 |
| 12 | Walsall | 15 | 20 |
| 13 | Oldham Athletic | 15 | 20 |
| 14 | Yeovil Town | 15 | 18 |
| 15 | Carlisle United | 15 | 17 |
| 16 | Brentford | 15 | 17 |
| 17 | Exeter City | 15 | 17 |
| 18 | Leyton Orient | 15 | 16 |
| 19 | Gillingham | 15 | 15 |
| 20 | Brighton and Hove Albion | 15 | 14 |
| 21 | Stockport County | 15 | 14 |
| 22 | Southampton | 15 | 12 |
| 23 | Tranmere Rovers | 15 | 10 |
| 24 | Wycombe Wanderers | 15 | 8 |
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Peter Beagrie expects a contrast of styles when Cardiff and Swansea clash at the Liberty Stadium.
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