Victories over Angelique Kerber, Caroline Wozniacki and Agnieszka Radwanska carried the Venezuela-born star to the final in SW19, although ultimately Serena Williams proved too good.
The run was enough to lift her in the world's top 10 for the first time and Muguruza continued her strong form through the second half of the season, a big title in Beijing helping her finish the season as world number three.
Prior to last season, her biggest moment had come at Roland Garros where she scored a shock win over Williams in 2014.
Like so many of the big names, she arrives in Melbourne with injury concerns surrounding her - a foot problem having led to a mid-match withdrawal in Brisbane earlier this month.
Now coached by Sam Sumyk, the man who helped Victoria Azarenka become world number one, Muguruza has plenty of weapons to launch a title assault - if fitness worries can be cast aside.