The Scot finished last season with five tournament victories in succession, culminating in World Tour Finals success over arch rival Novak Djokovic to claim the No 1 ranking to go with Wimbledon and Olympic gold.
He kicked off 2017 by reaching the final in Qatar, but then suffered a shock exit at the Australian Open and despite collecting his first title of the season in Dubai, little has gone right for the 30-year-old.
Murray did enjoy a run to the semi-finals at Roland Garros - where he lost to losing finalist Stan Wawrinka - but an abrupt end to his Queen's defence will have the two-time Wimbledon champion worried.
It was lucky loser Jordan Thompson - ranked 90 in the world - who knocked Murray out of Queen's in the opening round, and the Brit must now dig deep to rediscover the form which saw him win at the All England Club last year.
British tennis fans will be hoping the familiar sights of the All England Club can inspire Murray to a fourth Grand Slam triumph.