The name Williams yet again represents the hosts' top hope for the US Open, with Venus looking to go one better than at Wimbledon.
With her sister Serena absent and the field continuing to look wide open, the 37-year-old remains a major contender.
Indeed, she has reached the final of two of this year's Grand Slams, beaten by Serena in Australia before Garbine Muguruza dominated their Wimbledon showpiece.
Modest results in Toronto and Cincinnati have followed to reduce expectations somewhat, but the home fans will still be hoping she can land her first title of the year and 50th in total at Flushing Meadows.
Twenty years on from reaching the final on her tournament debut, the two-time champion returns as America's great hope again with every reason to believe she can make it a hat-trick of titles here.