Australia have suffered a double blow in their preparations for the ICC World Twenty20 in the Caribbean.
The Australians crashed to a shock one-run defeat in Tuesday's warm-up match against Zimbabwe in St Lucia - with the loss made worse by a tournament-ending injury to Brett Lee.
The 33-year-old quick bowler, who has been dogged by injuries in recent years, had taken 1-13 off four overs and completed the match.
However he complained off soreness in his forearm afterwards, with MRI scans revealing he had suffered a muscle strain.
The injury means Lee will miss the Twenty20 competition and Australia have asked the ICC's Technical Committee for permission to make a replacement to their squad.
Ryan Harris, coming off an impressive IPL campaign, was later confirmed as Lee's replacement in the 15-man squad.
"During yesterday's game against Zimbabwe Brett developed increasing right elbow pain and by the time he completed his final over the pain was significant," said team physio Alex Kountouris.
"At the conclusion of the innings it was obvious Brett had sustained an injury to one of the forearm muscles near the elbow and this was confirmed by a subsequent MRI scan.
"Due to the condensed nature of this tournament, Brett will not recover in time to take any further part and has therefore been withdrawn from the squad.
"This is not a recurrence of the elbow injury that recently required surgery but a new injury that will require specialist opinion upon his return to Australia."
Australia are desperate to pep up their attack after seeing Zimbabwe record a surprise win.
Elton Chigumbura's 76 off just 35 balls - including six sixes and five fours - had provided the backbone to Zimbabwe's total of 173-7. Mitchell Johnson took 4-23.
Australia's run chase fell agonisingly short as they were restricted to 172-7 despite 72 from opener David Warner and 49 by Michael Clarke.
Nick Knight says England must take more responsibility whilst batting to remedy their one-day international form.
Chris Gayle will be a big miss for West Indies during their one-day series with England.