Robert Lewandowski gave Bayern Munich a 1-0 home win over Cologne, and a nine-point lead over second-placed Schalke who beat Augsburg.
Borussia Dortmund's Bundesliga title hopes suffered another crushing blow as they slumped to a 2-1 defeat at Stuttgart.
Bayern Munich moved six points clear of Borussia Dortmund in the Bundesliga table with a 3-1 victory in Der Klassiker at Signal Iduna Park.
There were calls for Werder Bremen coach Alexander Nouri to be sacked after Sunday's 3-0 loss to Augsburg left them winless after ten games
Cologne's seemingly cursed start to the Bundesliga continued when Stuttgart scored in the fourth minute of injury time for a 2-1 win.
Borussia Dortmund continued their impressive start to the season as they secured a fourth straight win, seeing off Augsburg 2-1.
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