Steve Bruce fears Hull City could be without summer signing Robert Snodgrass for an extended period after the winger limped out of the 1-0 win at QPR.
Snodgrass, who joined Hull from Norwich, endured a disappointing debut as he was replaced before half-time at Loftus Road with a knee injury.
"Snodgrass is a concern," Bruce said. "He's twisted his knee. He's in a brace and crutches at the moment - touch wood he's not too bad.
"We fear ligament damage and if it is, it'll obviously be a long time but hopefully it's not."
Bruce was disappointed with referee Craig Pawson's decision to award QPR a penalty late on and believes the rule regarding handball needs to be clarified.
"The referees have got to get together and realise they're making a mockery of it - it's supposed to be deliberate," Bruce said.
"(James) Chester has got his hand by his side, the ball is a yard away and probably travelling at 50 miles per hour - what's he supposed to do?
"We need to stop all this nonsense and have a bit of common sense."
The hosts could have rescued a point six minutes from time when Chester was adjudged to have handled Justin Hoilett's cross but Allan McGregor palmed Charlie Austin's spot-kick to safety.
"Some days it just doesn't go your way," QPR boss Harry Redknapp said.
"You get a penalty late on and I think if we'd scored the penalty we had time to win the game, the momentum was with us.
"Some days you get the breaks and some days you don't."