Tottenham goalkeeper Hugo Lloris will be out for around two weeks, according to France head coach Didier Deschamps.
Lloris injured his groin in Spurs' 3-1 win over Real Madrid in the Champions League on Wednesday night.
The incident happened in the second half when Lloris collided with Sergio Ramos, but after receiving treatment he carried on for the rest of the game.
It means Lloris is out of the France squad for the fixtures against Wales on November 10 and Germany four days later, and he is likely to miss Tottenham's Premier League game against bottom-club Crystal Palace on Sunday.
Toby Alderweireld was also injured at Wembley as Spurs produced a superb performance against the European Champions to qualify for the Champions League last 16 with two games to spare.
Alderweireld suffered a hamstring injury during the first half and is a doubt for the north London derby on November 18.
On a more positive note, Harry Kane returned to the starting line-up against Real Madrid after suffering a minor hamstring injury against Liverpool and appeared to come through the match unscathed.
Mauricio Pochettino will now be forced to make a couple of changes for the game against Palace as Tottenham re-focus on their Premier League campaign.
Spurs are third in the table ahead of the weekend fixtures whilst Palace are three points adrift at the bottom.