Katie Taylor and Daniel Jacobs will both fight on a busy New York bill on April 28, live on Sky Sports.
Taylor will be looking to add the IBF women's lightweight title to her WBA crown when she faces Victoria Noelia Bustos in a unification fight, while the 'Miracle Man' takes on Maciej Sulecki, at the Barclays Center, Brooklyn.
Local heavyweight favourite Jarrell 'Big Baby' Miller (20-0-1-KO18) takes on former world title challenger Johan Duhaupas (37-4-KO24), with the Brooklynite hoping to become a mandatory challenger to WBC king Deontay Wilder.
Taylor won her title on the Anthony Joshua undercard in Cardiff in October, and is attempting to become a unified champion in her second visit to America.
Bustos (18-4-KO0), from Argentina, won her IBF title a year ago but is already a two-weight, three-time world champion.
"Victoria Bustos is one of the longest reigning champions in women's boxing so I'm expecting a very tough fight," said Taylor.
"I've been back in training camp in Connecticut since the beginning of the month so the hard work has started and I'm excited to have the chance to win another world title.
"Becoming unified champion is very important to me. Last year was great but I'm not really one for looking back and it's all about the next challenge.
"I believe that winning my first world title as a pro is just the start of it, I want to fight all the other champions and unify the lightweight division."
Jacobs (33-2-KO29), who is Matchroom USA's shining star, will be topping the New York bill and can take another step closer to regaining a world middleweight title, with unbeaten Pole Sulecki (26-0-KO10) standing in his way.
"I'm very excited to be back at Barclays Center, it always feels like home fighting there," said Jacobs.
"I'm looking forward to fighting Sulecki on April 28, he's an undefeated guy that I know will be looking to make a name for himself by beating me.
"I'm looking to have a great training camp and get myself focused to really put on a show for the Brooklyn fans come April 28."