Fulham will assess Tomas Kalas after the centre-back missed Saturday's 2-1 win at Derby because of a hip injury.
Whites boss Slavisa Jokanovic has no other injury worries as he looks to extend his side's 13-match unbeaten run in the Championship.
Meanwhile, Sheffield United boss Chris Wilder has called the club's decision to call off last weekend's clash with Burton, into question.
He said: "We wanted to play on Saturday and I was sitting at a game think we should be playing, but we weren't.
"The weather in the area has been pretty poor and we made a decision as a football club to postpone Saturday's game on Thursday.
"We now have to get the Burton game into the schedule quickly, but we trained over the weekend, including at the Lane on Sunday and we are looking forward to another cracking Championship game on Tuesday night."
Wilder also revealed that forwards David Brooks, Ricky Holmes and James Wilson will all travel to the capital after spells on the sidelines, but midfielder Paul Coutts (broken leg) remains a long-term absentee.
These sides haven't met at Craven Cottage in a league match since August 2006 in the Premier League - Fulham won 1-0.
The reverse fixture ended 5-4 to Fulham at Bramall Lane - the first instance of an away side winning 5-4 in a second tier match since August 1966 (Portsmouth 4-5 Birmingham City).
The Cottagers have won 26 points in 2018 (P10 W8 D2 L0), four more than any other Championship side.
Sheffield United have kept one clean sheet in 17 away Championship matches this season.
Ryan Sessegnon has been involved in 12 goals in his last 12 Championship games (10 goals, 2 assists).
Billy Sharp has been involved in five goals in his last four Championship appearances (four goals, one assist).
Fulham are flying, even more so at home. On their run of form, they aren't necessarily gatecrashing the playoffs, but to get themselves into the playoffs after a gradual rise has been superb. They had a good win against Derby on Saturday, with Mitrovic and Sessegnon at the fore once again so that's why I fancy them in this fixture.
Prutton predicts: 2-1 (15/2 with Sky Bet)