Arsenal and Manchester United have suffered from injuries most over the last six years, a Sky Sports study has found.
In total, Arsenal players have been sidelined for 10,285 days during seasons since the start of 2011/12, while Manchester United have lost 9,600 days.
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Sky Sports looked at every injury recorded by PhysioRoom.com of current Premier League clubs since the start of 2011/12, up to the most recent round of fixtures, and calculated the number of days missed during active seasons.
Liverpool host Everton live on Sky Sports this Saturday and the Merseyside clubs appear next on the injured list, with the Toffees missing 8,058 days and the Reds 8,044.
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Of the teams that have featured in the top flight throughout the period, Chelsea have had the shortest period of lay-offs with just 4,559 days.
Meanwhile, Swansea have lost the second fewest number of days with 5,111, followed by West Brom (5,851), Manchester City (6,023) and Stoke (6,607).
Total days of injured players during seasons since 2011/12
|West Bromwich Albion||5,851|
Sunderland have been hit hardest by injuries this term with 1,761 days lost so far, followed by West Ham (1,574), Hull City (1,434), Watford (1,388) and Crystal Palace (1,385).
In contrast, West Brom's impressive season has been boosted by a league low 389 days of injuries, while Chelsea's title tilt has benefited from just 444 days lost.
The Gunners have lost 1,038 days in total, losing Santi Cazorla (150 days), Aaron Ramsey (117 days) and Per Mertesacker (166 days) for extensive periods.
Manchester United players have missed 787 days, with Phil Jones (90), Luke Shaw (84), Henrikh Mkhitaryan (81), Eric Bailly (59) and Chris Smalling (58) out for long spells.
The longest lay-offs this term have been Stoke's Jack Butland, Everton's Muhamed Besic and Hull's Moses Odubajo, who have all missed the entire campaign so far.
Total days lost from injuries 2016/17
|Club||Days injured 2016/17|
|West Ham United||1,574|
|West Bromwich Albion||389|
Bournemouth's Jack Wilshere, on loan from Arsenal, has been the most injured Premier League player over the period.
The England midfielder has missed 884 days during the last six seasons - 879 days during his time at Arsenal - of which 606 days were from foot and ankle injuries.
Former Gunner Abou Diaby is second on the list with 858 days on the sidelines before his move to Marseille in 2015, followed by former Everton trio Darron Gibson (792), Tony Hibbert (768) and Steven Pienaar (744).
Next among the most injured are West Ham's Andy Carroll (723), Manchester United's Phil Jones (721), Manchester City's Vincent Kompany (647) and Liverpool's Daniel Sturridge (640).
Total days missed during seasons, since start of 2011/12
WORST MONTHS & SEASONS
December has been the worst month for injuries with 683 cases since 2011/12 - supporting arguments for a winter break in England.
Indeed, the next worst months have been January (597) and November (586), followed by September (569) and February (568).
The season of 2014/15 produced more injuries than any other during the period in our study with 1,192 recorded, compared with 857 so far this season.