Jose Mourinho says Willian and Pedro will definitely miss Chelsea's Premier League clash with Arsenal on Saturday.
The Blues boss confirmed the news after watching his side win 4-0 in their opening Champions League tie against Maccabi Tel Aviv.
Willian opened the scoring for the home side after 15 minutes but was forced off midway through the first-half after picking up a hamstring injury.
Pedro did not make the squad for the European fixture and is now definitely out for the vital clash at Stamford Bridge this weekend as well.
Diego Costa replaced Willian after 22 minutes and went on to win a penalty and score his first Champions League goal for Chelsea after his introduction from the bench.
Their opponents on Saturday, Arsenal, suffered a disappointing night in the Champions League, losing 2-1 to Dinamo Zagreb and also having Olivier Giroud sent off.