Eredivisie champions PSV made it two wins from two as Hector Moreno's goal secured a 1-0 victory over AZ Alkmaar, on Sunday.
The Mexico international converted a pass from fellow defender Jetro Willems in the 52nd minute at Philips Stadion.
Feyenoord also continued their 100 per cent start as Jens Toornstra scored one and made another in a 2-0 success over FC Twente.
The midfielder found the roof of the net after 23 minutes before his pass was fired home from 20 yards by Denmark international Nicolai Jorgensen 10 minutes from time.
Newly-promoted Go Ahead Eagles had to settle for a point in a 2-2 draw at home to NEC.
French striker Kevin Mayi scored twice for the visitors, either side of goals from Sander Duits and Estonia international Henrik Ojamaa.
A brace from Paul Gladon helped Heracles to a 3-1 success over Willem II.
Moroccan Iliass Bel Hassani put Heracles in front before Gladon put the result beyond doubt. Erik Falkenburg pulled a goal back eight minutes from time.