England openers Alastair Cook and Mark Stoneman survived a tricky five-over spell before the close as the tourists ended day two of their day-night tour match against a Cricket Australia XI with a lead of 65.
Joe Root's side quickly lost their last two wickets in the first session to be bowled out for 293 but soon had the CA XI in trouble at 57-5.
Half-centuries from Tim Paine (52) and Simon Milenko (50) helped CA recover to reach 233-9 before making their declaration late in the day, while James Anderson (2-30), Chris Woakes (2-48) and Mason Crane (3-78) impressed with the ball for England.
The day began with England 278-8 but Ball was soon bowled by Gurinder Sandhu and Daniel Fallins trapped Anderson lbw to complete his five-for and put the visitors' bowlers to work.
An economical opening spell from Anderson built the pressure but it was the other England seamers who initially reaped the rewards, Woakes striking twice with Ball (1-5) and Craig Overton (1-40) also chipping in.
Crane claimed the other in that impressive opening burst but a stand of 86 between Paine and Matthew Short (45) slowed England's progress.
Anderson returned to account for both, only for Milenko to come in and take the attack to England and move briskly to his half-century.
His shot-filled knock was brought to an end by Crane, who also had Sandhu lbw three balls later with the declaration coming just overs later.
Left-armer Jackson Coleman rapped both Cook (1no) and Stoneman (4no) on the pads, drawing loud appeals from behind the stumps, but the umpire was unmoved on each occasion and with the new ball offering far less movement under the lights than on the first evening, CA were unable to the early breakthrough they craved.