Misbah-ul-Haq and Younis Khan begin their final Test series on Friday when Pakistan take on West Indies in the first of three Sky Live matches, at Sabina Park.
The pair, who have 72 and 115 caps respectively, both scored single figures in the tourists' drawn three-day match against a West Indies President's XI.
Younus - who requires just 23 more runs to become the first Pakistani to reach 10,000 Test runs - and Misbah have scored 44 hundreds between them and will hope to inspire their team to a series win following a slump of six defeats.
Wahab Riaz and Mohammad Aamir are set to lead Pakistan's attack after Hasan Ali picked up an injury in the warm-up match, while fast bowler Mohammad Abbas, 27, could earn his first Test cap.
West Indies have included Kieran Powell and the uncapped pair of Vishaul Singh and Shimron Hetmyer in their squad of 13.
Hetmyer, captain of the victorious team at last year's Under-19 World Cup in Bangladesh, and fast-medium bowler Miguel Cummins are most likely to be omitted from the final eleven.
West Indies (possible): Jason Holder (capt), Kraigg Brathwaite, Kieran Powell, Shai Hope, Vishaul Singh, Jermaine Blackwood, Shane Dowrich, Roston Chase, Devendra Bishoo, Alzarri Joseph, Shannon Gabriel.
Pakistan (possible): Misbah-ul-Haq (capt), Azhar Ali, Ahmed Shehzad, Babar Azam, Younis Khan, Asad Shafiq, Sarfraz Ahmed, Mohammad Aamir, Wahab Riaz, Yasir Shah, Mohammad Abbas.