Australia can at least call on Twenty20 specialists Shaun Marsh, Aaron Finch and James Faulkner, though Adam Voges - who hit a century in the fifth and final one-dayer on Sunday - is a doubt due to a hamstring problem.
West Indies, meanwhile, are waiting to see if Chris Gayle will be fit to feature; the opener has not played since suffering a side injury during the third ODI.
Visiting skipper Darren Sammy hopes his side, with or without Gayle, can find the kind of form in the shortest format that saw them triumph in the ICC World Twenty20 in Sri Lanka last year.
"We have to come and play like true champions. We are the world champions and we want to showcase our skills and show the people of Australia what we have," Sammy said.
"We did the job very well in Sri Lanka last year. The last time we played against Australia in this format we completely outplayed them so that is the kind of motivation we will carry into the match.
"The people over here in Australia have been very supportive of us and we have not demonstrated our very best cricket for them to see, so we want to give them something special before we head back home."
