Rotherham and Exeter battled to a 1-1 draw at the New York Stadium.
Exeter moved 10 points clear of the League One relegation zone as they made it back-to-back home wins with a 2-0 victory over fellow strugglers Mansfield.
Exeter picked up their first home League One win since Boxing Day with a 2-0 victory over fellow strugglers Shrewsbury.
Reading's League One play-off hopes suffered a setback when they were held to an uninspiring goalless draw at home to relegation-threatened Exeter.
Sonny Cox scored his first goal in almost a year to rescue a point for Exeter in their 1-1 League One draw with relegation rivals Northampton at St James Park.
Charlton made it five successive home wins in League One as they swept aside Exeter 3-0.
Exeter recorded their first Sky Bet League One win since Boxing Day with a 1-0 success at Cambridge piling further pressure on the bottom club.
Nottingham Forest survived a huge FA Cup scare against 10-player Exeter to win a penalty shoot-out after drawing 2-2 at St James Park.
Plymouth's reward for knocking out Liverpool is a trip to Manchester City in the FA Cup fifth round while holders Manchester United will play Fulham.
Stevenage made it four wins in a row and three in League One with a comprehensive 4-1 win at home to Exeter.
Azeem Abdulai struck a hat-trick as Leyton Orient moved into the League One play-off places with a 6-2 thrashing of Exeter.
Blackpool picked up their first league win since December 14 as their first-half blitz earned them a 3-1 win at Exeter in Sky Bet League One.
In Behind the Whistle, former Premier League referee Chris Foy goes through a selection of key match decisions from the weekend EFL action.
Millenic Alli scored the rebound of his saved penalty to salvage a late 1-1 draw for Exeter at Peterborough to extend the home side's winless run in Sky Bet League One.
Birmingham maintained their lead at the top of the Sky Bet League One table with a 1-0 win over Exeter at St Andrew's.
Largie Ramazani's second-half header sealed Leeds a 1-0 win and ensured they avoided an FA Cup upset against Yorkshire rivals Harrogate.
Holders Manchester United will host Leicester City, while Aston Villa will play Tottenham in the fourth round of the FA Cup.
Aaron Morley marked his return to Bolton with a stoppage-time winner in their 2-1 League One success at Exeter.
Aaron Morley scored an injury-time penalty in what was potentially his last game for the club as Wycombe left it late to beat Exeter 2-1.
Crawley Town striker Tola Showunmi couldn't believe his luck when Exeter City's goalkeeper threw him the ball to set up an easy goal.