Barcelona slumped to a 1-0 home defeat by Rayo Vallecano which pushed leaders Real Madrid a step closer to the La Liga title.
Bundesliga leaders Bayern Munich slipped to a shock 4-2 defeat at VfL Bochum on Saturday, conceding all four goals in the first half.
The Copa del Rey derby match between Real Betis and Sevilla was suspended after a pole hurled from the stands hit Sevilla player Joan Jordan in the head on Saturday.
Bayern Munich extended their Bundesliga lead to six points with Jamal Musiala on target as they beat Mainz 2-1, while Borussia Dortmund were held by Bochum.
Memphis Depay and Philippe Coutinho scored late on at Villarreal as Barcelona won 3-1 to finally end their winless streak away from home under new coach Xavi.
Przemyslaw Frankowski earned Lens their first victory over Lille for 15 years in a derby marred by crowd trouble, while Bayern Munich and Inter both racked up big wins.
| # | Team | Pl | GD | Pts |
|---|---|---|---|---|
| 1 | Hoffenheim | 0 | 0 | 0 |
| 1 | Hertha | 0 | 0 | 0 |
| 1 | Bochum | 0 | 0 | 0 |
| 1 | Stuttgart | 0 | 0 | 0 |
| 1 | Mainz | 0 | 0 | 0 |
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