Juventus maintained their perfect record in Serie A as a 2-0 home win against Bologna gave the Turin club their best start to a season in 88 years.
Inter Milan's woes in Serie A were compounded with a shock 1-0 defeat to Parma on Saturday ahead of their Champions League opener against Tottenham.
Napoli missed the chance to go level with Serie A leaders Juventus after tumbling to a 3-0 defeat at Sampdoria.
Crotone beat Lazio 3-1 on the final day to ensure survival, as Empoli went down after losing at already-relegated Palermo.
Napoli took advantage of Roma's derby defeat to close to within one point of second place in Serie A with victory over Inter Milan.
Juve extended their lead at the top of Serie A after beating Pescara 2-0 to strengthen their grip on a sixth straight Scudetto title.
Gonzalo Higuain reached 15 goals for the Serie A season as Juventus reinforced their position as leaders with a 2-0 win over Sassuolo.
Francesco Totti made his 600th Serie A appearance as Roma moved up to second spot with a 3-0 win over Chievo.
Juventus celebrated winning the Serie A title for the fifth year in a row by beating relegation-threatened Carpi 2-0.
Juventus are closing in on a fifth consecutive Serie A title after emerging victorious from a gritty game with Fiorentina.
Juventus moved a step closer to a fifth straight Serie A title after pulling nine points clear with a 4-0 win over Palermo.
Paul Pogba sustained Juventus' march towards a fifth straight Serie A title by completing a 2-1 comeback victory over AC Milan.
Juventus have moved a step closer to a record-equalling fifth successive Serie A title after their closest rivals Napoli lost at Udinese.
Goalkeeper Gianluigi Buffon added another record to his decorated career during Juventus' 4-1 win over local rivals Torino.
Gonzalo Higuain's penalty saw Napoli squeeze past Palermo 1-0 and maintain their pursuit of the Serie A title.
Juventus restored their three-point advantage at the top of Serie A with a 2-0 win at Atalanta on Sunday.
Juventus threw down the gauntlet to Serie A title rivals Napoli by pulling four points clear at the top of the table.
Roma routed Palermo without Francesco Totti on Sunday, while Fiorentina kept pace in the Serie A title race.
Juventus moved above Napoli at the top of Serie A after Simone Zaza's late goal secured a 1-0 win over the Azzurri.
Gonzalo Higuain scored a late penalty to give Napoli a 1-0 victory over Carpi on Sunday and keep them top of Serie A.