It's all change in the NFL so in whose hands do you place your hopes of going to the Super Bowl?
Enter the game to have a chance of going to the Super Bowl!
It's all change in the NFL this week, with the Bears and Bucs heading off to London and a host of changes at quarterback coming up, so in whose hands do you place your hopes of going to the Super Bowl next year? Read on for the answers...
Out go Donovan McNabb, Jason Campbell and Kyle Orton, and in come Christian Ponder, Carson Palmer and, of course, Tim Tebow - who will be looking for a welcome home party in Florida against the awful Miami Dolphins.
All these new options might have your mouse finger twitching ready to select them, but they would be best watched for this week, and sticking to the tried and tested usuals - apart from the great Tom Brady who sits out this week on a bye.
Besides, Fantasy Football is not as quarterback driven a league as the NFL, with last week's top scorer being Ahmad Bradshaw, and the next best being the New York Jets defence! Just shows what a tough task it is predicting who to pick each week.
Despite this, we'll give it a go anyway and try and give you a helping hand to Indianapolis and Super Bowl XLVI.
Week Seven pick-ups
Quarterbacks
Must have: There's a lot of talk about match-ups in fantasy, but week-in, week-out Aaron Rodgers performs a hugely impressive level, so he'd be a decent start on any given Sunday - and saying that, he faces the Vikings who have a rookie at quarterback and rolled over and had their bellies tickled by Jay Cutler and his underwhelming Bears! Drew Brees could be another option though, as he has the taking-candy-from-a-baby match-up at home against the winless Colts, while Tony Romo gets the winless Rams.
Solid starter: Washington rank sixth in overall defence, but there should still be enough in a home game for Carolina quarterback Cam Newton to again justify his $2m price tag, which now looks the biggest bargain of the season. Even if the Skins keep Steve Smith and the receivers quite, Newton is a big man to pull down so a rushing score is always on the cards.
Steer clear: Matt Ryan had a decent week last week, but a home game against Carolina is not the same as going into the Lions' den, literally in Detroit, and facing a team smarting after their first loss of the season. Detroit has a fierce pass rush, led by the ferocious Ndamukong Suh and the Falcons have allowed 40 QB hits this season, this could get uglier than Jim Schwartz's handshake battle with Jim Harbaugh last week.
Running backs
Must have: Darren McFadden will be asked live up to his name, well the 'Run' part in Run DMC as the Raiders ease in new QB Carson Palmer, and there's no reason to force Palmer to throw it early with them facing the Chiefs who have conceded six rushing scores over the first five weeks. The Jags have relinquished 140 yards a game over their last three games and now get Baltimore and Ray Rice, who can also pile up the yards on short passes as well.
Solid starter: Mark Ingram is only a $2m purchase and the Saints should have plenty of touches to go around against the Colts, and their rookie RB has three scores in four weeks with just nine touches each game. Veteran Earnest Graham could give you something to shout about at Wembley as he most likely steps in for LaGarrette Blount again against a Bears team that allows the second most yards-per-carry.
Steer clear: Beanie Wells has had a week off to rest any lingering injury worries, but don't expect his recent lofty heights against the Steelers who are slowly getting back to their old selves. Chris Johnson may also have finally got up to speed after a week off, but at $4m he may not yet be back to elite status so he is best watched for another week at least.
Wide receivers
Must have: Detroit's Calvin Johnson has an NFL-high nine touchdowns and enjoys a favourable match-up this week against an ordinary Atlanta defence. 'Megatron' is close to unstoppable when the Lions get into the red zone and there is no reason to think he will not enjoy another excellent day at Ford Field on Sunday. With New England's Wes Welker on a bye, Johnson is the clear standout pick at wide receiver this week.
Solid starter: It doesn't pay to overthink fantasy selections. Carolina's Steve Smith trails only Welker in terms of receiving yards this season and, at $2million, represents a snip. Smith, a four-time Pro Bowler, is rolling back the years in tandem with big-armed rookie quarterback Cam Newton and, despite the Panthers being up against one of the better secondaries - Washington - this week, is worth every penny.
Steer clear: Of the $4million options, San Diego's Vincent Jackson is the one to swerve. The Chargers are in the New Meadowlands taking on the New York Jets and Jackson is likely to find himself marked all afternoon by Darrelle Revis, one of the few genuine shutdown corners in the league. A change of scenery is unlikely to do much for the prospects of $3million Brandon Lloyd. Lloyd was traded from Denver to the St Louis on Tuesday and will make his Rams debut against the Dallas Cowboys in Arlington. Two things you need to know here - the Rams are 0-5 and quarterback Sam Bradford is suffering from a high left ankle sprain. If Bradford is ruled out, AJ Feely - whose last start was in the 2007 season - will be throwing to Lloyd.
Best of the rest
Tight ends: This one is really simple. New Orleans' Jimmy Graham is towering over his fellow tight ends in fantasy terms, only two wide receivers - Welker and Smith - have more receiving yards. Graham's Saints have a week seven date at home against the winless Indianapolis Colts. Get him in the line-up for $2million.
Defences: Dallas have the fifth-ranked defence in the league - first against the run, 14th against pass - and should enjoy another productive day at home to the beleaguered St Louis Rams. Even if Bradford plays through the pain, he is set for a difficult time behind an offensive line that has allowed an NFL-high 21 sacks already this season. Cowboys pass rushers DeMarcus Ware, who has seven sacks in five games, and Anthony Spencer will be scenting blood.
Kickers: If you are going to splash out $2million on a kicker then go for Green Bay's Mason Crosby. There are two factors in his favour; firstly the Packers are at Minnesota which means Crosby will be kicking indoors. And secondly, the 1-5 Vikings have the second-best red zone defence in the NFL this season, therefore Crosby might get more field-goal action than usual. Another decent $2m option is Pittsburgh's Shaun Suisham, who will benefit from kicking in hot desert air in Arizona. Among cut-price $1million men, why not take a chance on Dallas kicker Dan Bailey?