Monday 19 March 2018 16:33, UK
Munster have ruled fly-half Tyler Bleyendaal and scrum-half Duncan Williams out for the rest of the season, while there is also concern surrounding Ireland star Keith Earls.
Earls limped off in the 73rd of Ireland's Grand Slam victory over England at Twickenham on Saturday with a knee injury.
Munster have confirmed he is set for a scan and will "require specialist assessment to determine the full extent of the injury".
New Zealand native Bleyendaal has been limited to seven appearances for Munster this season as he has battled a neck injury, while Williams was injured in training last week.
Munster confirmed in a statement both have undergone season-ending surgery, while Simon Zebo, Alex Wootton and Jean Kleyn all sustained injuries against Edinburgh, but Ireland international hooker Niall Scannell is nearing a return to action after missing the Six Nations.
"Bleyendaal required surgery in a bid to rectify ongoing symptoms with his neck, while Williams underwent surgery after sustaining facial injuries during a training session last week," the statement said.
"Following Friday night's defeat against Edinburgh in Murrayfield, Simon Zebo (hamstring) and Alex Wootton (hip flexor) will be reviewed by the medical department today, while Jean Kleyn is following return-to-play protocols after sustaining a concussion.
"Niall Scannell returns to full training this week as he recovers from a rib injury sustained against Glasgow Warriors at the end of February."