Wednesday 1 November 2017 19:31, UK
Jonny May is set to miss England's opening autumn international against Argentina on Saturday week after sustaining a hamstring injury during the squad's training camp in Portugal.
May pulled up in Tuesday's practice session in Vilamoura to further limit Eddie Jones' wing options after Elliot Daly and Jack Nowell were ruled out of the majority of the Twickenham program due to respective knee and cheekbone problems.
However, the Leicester Tigers man is expected to be fit for England's game against Australia on November 18, which is live on Sky Sports.
England forwards coach Steve Borthwick told Sky Sports News on Wednesday: "He picked up a couple of knocks in training this week, he's hurt his hamstring. It means he's likely to be doubtful for Argentina.
"Our medical team are very positive he will be fit for Australia. One thing I would say about Johnny - since I've got to know him working with the team, his preparation is meticulous.
"I've already seen it, just with everything he's doing to get back fully fit as quick as possible."
It leaves England with only three fit players in the position for the visit of the Pumas in Anthony Watson, Denny Solomona and Semesa Rokoduguni.
There are minor concerns over Solomona and Rokoduguni, but the pair are expected to shake off an Achilles issue and dead leg respectively.
Jones had hoped to rest Watson due to his involvement in the British and Irish Lions Test series against New Zealand during the summer, but he must now revise those plans and start him in a back three that will also include either Solomona or Rokoduguni.
Fly-half Marcus Smith is to return home after spraining his foot and Joe Launchbury is nursing a knee problem that will prevent him from training until Friday.
Borthwick added: "Marcus hurt his toe, his foot, so he's heading back home tomorrow to London to get further investigation on that. I don't think it's that serious but we want to make sure it's fully analysed.
"Joe Launchbury hurt his knee but we expect him to be fully fit and training by the end of the week."
England were forced to adjust their training schedule on Wednesday to account for the number of injuries of varying severity and the decision to rest the Lions players, which meant 14 of the 33 who assembled in Portugal were unable to take part.
Losing May would be a significant blow as the 27-year-old has been in blistering form since swapping Bath for Leicester this season, crossing 10 times in nine matches for the Tigers.