Younus Khan flayed England for 218 before Yasir Shah cemented Pakistan's position of dominance with three key wickets on day three of the fourth Test, at the Oval.
Younus, 101 overnight, registered his sixth score of 200 or more in Test cricket - reaching his double-century with a six and striking 31 fours and four maximums off 308 balls in total, having scored just 122 runs in his six previous innings.
The 38-year-old propelled Pakistan to 542 and a first-innings lead of 214 before Yasir got to work, knocking over Alex Hales (12), James Vince (nought) and Joe Root (39) after Alastair Cook (seven) had nicked off against Wahab Riaz to leave the home side 75-4.
Gary Ballance (four not out) and Jonny Bairstow (14no) ensured there was no further loss before stumps, which the home side reached on 88-4, still 126 in arrears.
England bowled well in the morning session after Pakistan resumed on 340-6, just 12 in front - James Anderson conceding just 10 runs off six overs - but found the seventh-wicket stand between Sarfraz (44) and Younus tough to crack.
Bustling Sarfaz contributed 40 to a half-century stand off 110 balls, bristling with intent until he pushed too hard at a Woakes delivery and was well-taken one-handed by Bairstow.
The breakthrough was Woakes' 26th scalp of the series and ended a 77-run partnership that tilted the tenor of the Test firmly in Pakistan's favour.
Steven Finn thought he had dismissed Younus lbw for 133 shortly afterwards but the batsman reviewed umpire Bruce Oxenford's decision and replays showed the ball going over.
Cook turned to his spinner Moeen Ali just before lunch and Younus quickly cashed in, crashing two fours before a pulled boundary off Broad after the interval took the veteran to his 12th score of over 150 off 231 balls.
The skipper did little to help England's cause three overs later when he grassed an edge at slip offered by Wahab but his blushes were spared in the same over when the batsman advanced only to be stumped, the ball cannoning out of Bairstow's gloves and onto the wicket.
England's hopes of polishing off the tail quickly where thwarted by Mohammad Amir (39) who got off the mark by slog-sweeping his 24th ball, bowled by Ali, for six moments after Younus had surged past 200 by pummelling Ali over mid-wicket - his second six off the spinner in successive overs.
Amir surpassed his previous Test best of 30, made against Australia in Hobart in 2010, unfurling some attractive drives on the way and helping amass 97 for the ninth wicket with Younus.
Anderson finally ended the partnership with a full, fast off-spinner that struck Younis on the pad - the review failing this time as replays showed the ball clipping leg. England's torment came to an end soon after when Sohail Khan was caught at mid-on off Finn.
Only six times in the history of Test cricket has a team recovered from conceding a first-innings deficit of over 200 to win and England's openers were quickly under pressure as Amir and Sohail turned in testing new ball spells but it was Wahab who nipped out Cook (seven), finding the edge with his second legitimate delivery.
Hales' disappointing series with the bat ended with another low score when he was plumb lbw to Yasir's sixth ball - the spinner having the final say in an on-going spat that began on day one when he claimed a catch contested by the opener.
That left Hales with a series average of just 18.12 but Vince's return of 22.57 was no more impressive, the Hampshire batsman falling for a third-ball duck as he drove loosely at Yasir.
Root played with a freedom that belied the match position, posting his 4,000th career-Test run when he reached 34 - at 25 years and 227 days the fourth youngest to reach the milestone after Sachin Tendulkar, Cook and Kane Williamson.
But, as in the first innings, he could not build on his start and was lbw to one that fizzed through without turning.
Watch highlights of day three from 9pm on Sky Sports 2, followed by the Verdict at 10pm on the same channel. Live coverage of day four begins at 10.30am on Sunday on Sky Sports 2 after Cricket Writers on TV.