Fin Smith knocked over a last-minute penalty as Northampton beat league leaders Bath 35-34 in a pulsating game of nine tries.
Ollie Lawrence has apologised for his role in an incident that led to his England team-mate Alex Mitchell being sin-binned in Bath's defeat at Northampton.
Tom Willis surged over for two tries as Saracens dispatched second-placed Bristol Bears in a 35-26 victory in the Gallagher Premiership on Saturday.
Harlequins ended their three-game winless run in the Gallagher Premiership with a 38-14 victory over Newcastle at Kingston Park.
Exeter claimed their first Gallagher Premiership victory of the season as they edged out West Country rivals Gloucester 22-15 at Sandy Park.
Bath inflicted a record Gallagher Premiership defeat on 14-man Saracens as they powered to a 68-10 victory at the Recreation Ground.
Sale Sharks pulled off a brilliant 38-0 victory over Bristol Bears at Ashton Gate to move into the Gallagher Premiership play-off places.
Saracens climbed up to third place after a comfortable victory over Northampton in the Gallagher Premiership.
Bristol sent out a major title statement as Pat Lam's men set a new Premiership record in a thumping 54-24 win over Leicester at Welford Road.
Gloucester beat an out-of-sorts Harlequins at Kingsholm as the visitors were blanked in a league game for the first time in a decade.
Marcus Smith has signed a new long-term contract that will keep him at Harlequins until at least 2028.
Defending champions Northampton suffered a shock defeat to Gloucester, while Bath returned to top of the Premiership and Sale beat Leicester.
Harlequins said goodbye to Joe Marler and their reputation as one of the Gallagher Premiership's meanest defences as irresistible Bristol stormed The Stoop 48-24.
Sale Sharks and England forward Jonny Hill has received a 10-week ban - with four weeks suspended - after accepting a charge that he abused a spectator.
Henry Slade proved his fitness ahead of England's Autumn Nations Series opener but could not prevent Exeter from suffering defeat by Harlequins.
Six-try Bath powered their way to a bonus-point victory over Sale Sharks to round off the first block of Gallagher Premiership matches in style.
Bristol regained top spot in the Gallagher Premiership as centre Kalaveti Ravouvou scored two tries to underpin a 31-23 victory over champions Northampton at Ashton Gate.
Alex Lozowski booted a penalty with the game's final kick as Saracens claimed a thrilling 37-35 Gallagher Premiership victory over Bristol at Ashton Gate.
Northampton bounced back from their derby disappointment in style as they trounced Sale while Newcastle earned their first Premiership victory in over a year.
Tom Roebuck scored twice as Sale cruised to a thumping 43-10 bonus-point win to condemn Newcastle to a 25th successive Premiership defeat.