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Serena starts against Glatch

Image: Williams: Bidding for a fourth US Open title at Flushing Meadows

Defending champion Serena Williams will kick-off the defence of her US Open title against American wildcard Alexa Glatch.

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Holder begins defence against American wildcard

Defending women's singles champion Serena Williams will kick-off the defence of her US Open title against American wildcard Alexa Glatch. The three-time champion at Flushing Meadows has been drawn in the same half as sister Venus and the pair could meet at the semi-final stage. World number one Dinara Safina, who is still chasing her first Grand Slam title, has been drawn against Australian wildcard Olivia Rogowska in the opening round while Venus takes on another Russian, Vera Dushevina. Former champion Maria Sharapova, seeded 29, begins her campaign against Bulgarian Tsvetana Pironkova and could face fourth seed Elena Dementieva in round three. Belgian former world number one Kim Clijsters, who returned to the tour this month after a two-year layoff, will play Viktoriya Kutuzova of Ukraine in round one. The 2005 champion could play Venus Williams if both players progress to the fourth round. Elsewhere, 2004 US Open champion Svetlana Kuznetsova faces a first round duel with German Julia Goerges, while beaten 2008 finalist Jelena Jankovic kicks-off against Roberta Vinci.