Ben Foden scored a last-gasp try to snatch a 27-23 victory for Northampton against Harlequins.
Jimmy Gopperth slotted a late penalty to earn lethargic Wasps a 9-8 victory over Newcastle at the Ricoh Arena.
Sale ended Leicester's unbeaten Aviva Premiership home record with a hard-fought 10-3 victory at Welford Road.
James Hook kicked five penalties as Gloucester came back in difficult conditions to beat West Country rivals Bath 15-11.
All the team news ahead of Saturday's Aviva Premiership action, including Andy Goode's trip to Wasps with Newcastle.
Topsy Ojo makes his 250th appearance for London Irish on Sunday when they face fellow strugglers Worcester.
Stuart Hooper returns for Bath while John Afoa boost Gloucester's pack for their derby clash on Friday.
Wasps have signed Tonga international Siale Piutau until the end of the season.
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Alex Payne is tipping Eddie Jones' England to win the Six Nations at the first time of asking.
Jamie Weir attended the Six Nations launch and asked all six captains for their player to watch in this year's championship.
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We preview the 2016 Six Nations Championship as England begin life under Eddie Jones and Ireland eye a third successive title.
Barbarians v South Africa
5th November 2016
England begin the Eddie Jones era with victory light years ahead of development in terms of importance, says Stuart Barnes.
Will Greenwood says Dylan Hartley's slate is now clean as he starts his tenure as England captain under Eddie Jones.
Will Greenwood has championed Exeter No 8 Thomas Waldrom as his side book their place in the Champions Cup quarter-finals.
Stuart Barnes says the appointment of Dylan Hartley as captain represents a 'major symbolic shift' in English rugby.