The 2017 Eredivisie winners Feyenoord were shocked 2-0 by De Graafschap in their first game of the new league season.
Huddersfield Town have agreed to sign Juninho Bacuna from FC Groningen for an undisclosed fee.
ADO Den Haag and Heerenveen will join Vitesse and Utrecht in the play-offs for the last Europa League spot despite mixed fortunes on the final day.
Former Eredivisie champions FC Twente have been relegated from the league after a thumping 5-0 defeat at Vitesse on Sunday.
David Neres scored twice as Ajax moved a step closer to Champions League qualification with a 4-1 win at home to VVV-Venlo.
PSV Eindhoven secured their 24th Eredivisie title after beating Ajax 3-0 on Sunday.
Ajax celebrated their 118th birthday in memorable fashion with a 5-2 thrashing of Sparta Rotterdam.
Ajax's hopes of winning the Eredivisie title suffered another setback as they were beaten 3-2 at Vitesse Arnhem on Sunday.
AZ Alkmaar kept the pressure on second-placed Ajax by coming from behind to beat the Eredivisie's bottom club Sparta Rotterdam 2-1.
Ajax reduced the gap to Eredivisie leaders PSV to seven points following a hard-fought 2-1 victory against FC Twente.
PSV Eindhoven extended their lead at the top of Eredivisie to eight points with a hard-fought 2-0 win at Twente.
Ajax beat 10-man Feyenoord 2-0 in De Klassieker as PSV scored a last-gasp winner to maintain their five-point lead at the top of the Eredivisie table.
Feyenoord romped a record derby win over Sparta Rotterdam, stunning their rivals with a 7-0 away success.
PSV Eindhoven conceded a last-gasp equaliser as FC Groningen fought back to draw 3-3 in the Eredivisie.
Eredivisie leaders PSV Eindhoven suffered a first league defeat in three months as Ajax hit them with three second-half goals to win 3-0 at the Amsterdam Arena.
Ajax missed the chance to close the gap on league leaders PSV after conceding a last-gasp equaliser in a 3-3 draw at lowly FC Twente.
Wins for PEC Zwolle and Feyenoord on Saturday kept both teams in the mix for the Eredivisie's European places.
Nicolas Isimat-Mirin grabbed a dramatic winner as Eredivisie leaders PSV stretched their winning run to eight with a 1-0 victory at Zwolle.
Wout Weghorst scored and was later sent off as AZ Alkmaar held on for a 3-2 comeback victory against struggling Willem II.
Hirving Lozano and Jurgen Locadia each scored twice as PSV Eindhoven restored their five-point lead at the top of the Eredivisie.
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