Naomi Broady, Tara Moore and Agnieszka Radwanska out of AEGON Classic

Two British players and two of the leading seeds were opening round victims on Wednesday at the Aegon Classic in Birmingham.

Heather Watson made it safely through her first round match on Monday but Naomi Broady and Tara Moore failed to follow her into the last-16 on Wednesday after rain in the Midlands finally relented.

Broady won the opening set of her match against Australia's Daria Gavrilova, but she could not maintain her momentum and eventually crashed out 4-6 6-2 6-3.

It was a similar story for Moore, who reached the quarter-finals in Nottingham last week before losing to China's Saisai Zheng.

Moore took an early lead in her match against Tamira Paszek of Austria, but the 23-year-old was unable to match her more experienced rival as she exited the tournament 4-6 6-4 6-4.

There was a major surprise for top seed Agnieszka Radwanska, who failed to progress past her first match.

Radwanska, a former Wimbledon runner-up, had intended to use the grass court event as a springboard for another assault on the oldest Grand Slam title but she was beaten 7-5 4-6 6-3 by America's CoCo Vandeweghe.

"I don't think I played so bad today - she was just really good," said Radwanska.

And fourth seed Belinda Bencic is also out, having been forced to withdraw from her match against Romania's Irina-Camelia Begu.

Bencic, whose season has been plagued by injury, took a tumble in the first game and suffered a thigh injury she later admitted should have seen her withdraw straight away - "I continued playing more than I should have," she said.

She carried on but struggled to get around the court and eventually pulled out with Begu 6-4 4-3 in front.

The return of rain late in the day meant British No 1 Johanna Konta was unable to start her opening match against Japan's Misaki Doi.