Sunday 27 March 2016 14:32, UK
Three of Harlequins' England stars return for their trip to Northampton while George North starts for Saints.
Andy Goode will make his final Newcastle appearance when the Falcons host Wasps, with Manu Tuilagi returning to the Leicester midfield for their visit to Sale.
Newcastle Falcons v Wasps (1pm)
Andy Goode has been named on the Newcastle bench for his final game before ending a three-month stint at Kingston Park and returning to the retirement ranks.
The Falcons show four changes following last week's game at Bath, with wing Alex Tait, centre Adam Powell, scrum-half Michael Young and lock Sean Robinson all starting.
England pair Elliot Daly and Joe Launchbury both return for Wasps as they look to continue their title play-off push. Daly partners Siale Piutau in midfield, while Launchbury forges Wasps' second-row combination alongside Kearnan Myall.
Elsewhere, George Smith features in the back row and there is also a start for wing Josh Bassett.
Newcastle Falcons: 15 Simon Hammersley, 14 Alex Tait, 13 Chris Harris, 12 Adam Powell, 11 Marcus Watson, 10 Mike Delany, 9 Michael Young; 1 Rob Vickers, 2 George McGuigan, 3 Taione Vea, 4 Calum Green, 5 Sean Robinson, 6 Mark Wilson, 7 Will Welch (c), 8 Nili Latu.
Replacements: 16 Scott Lawson, 17 Alex Rogers, 18 Mike Cusack, 19 Ally Hogg, 20 Sinoti Sinoti, 21 Sonatane Takulua, 22 Andy Goode, 23 Belisario Agulla.
Wasps: 15 Rob Miller, 14 Christian Wade, 13 Elliot Daly, 12 Siale Piutau, 11 Josh Bassett, 10 Jimmy Gopperth, 9 Dan Robson; 1 Matt Mullan (c), 2 Ashley Johnson, 3 Jake Cooper-Woolley, 4 Joe Launchbury, 5 Kearnan Myall, 6 Thomas Young , 7 George Smith, 8 Sam Jones.
Replacements: 16 Carlo Festuccia, 17 Tom Bristow, 18 Phil Swainston, 19 James Cannon, 20 Nathan Hughes, 21 Craig Hampson, 22 Ruaridh Jackson, 23 Brendan Macken.
Northampton Saints v Harlequins (3pm)
England captain Dylan Hartley, who was carried off during the Six Nations finale against France last weekend, does not feature for Northampton, with Saints boss Jim Mallinder making five changes.
Centre Luther Burrell, wing George North and fly-half Stephen Myler all start, along with prop Kieran Brookes and flanker Tom Wood.
England's Mike Brown, Joe Marler, Jack Clifford and Danny Care all feature in Quins' starting line-up, with scrum-half Care making his 200th first-team appearance.
Wales centre Jamie Roberts also plays following his Six Nations commitments, while England flanker Chris Robshaw has been named among the replacements.
Northampton Saints: 15 Ben Foden, 14 Ken Pisi, 13 George Pisi, 12 Luther Burrell, 11 George North, 10 Stpehen Myler, 9 Lee Dickson (c); 1 Alex Waller, 2 Mikey Haywood, 3 Kieran Brookes, 4 James Craig, 5 Christian Day, 6 Jamie Gibson, 7 Tom Wood, 8 Teimana Harrison.
Replacements: 16 Reece Marshall, 17 Campese Ma'afu, 18 Paul Hill, 19 Courtney Lawes, 20 Sam Dickinson, 21 Kahn Fotuali'I, 22 JJ Hanrahan, 23 Harry Mallinder.
Harlequins: 15 Mike Brown, 14 Charlie Walker, 13 Joe Marchant, 12 Jamie Roberts, 11 Tim Visser, 10 Ben Botica, 9 Danny Care (c); 1 Joe Marler, 2 Joe Gray, 3 Will Collier, 4 George Merrick, 5 James Horwill, 6 Jack Clifford, 7 Luke Wallace, 8 Nick Easter.
Replacements: 16 Dave Ward, 17 Mark Lambert, 18 Kyle Sinckler, 19 Mat Luamanu, 20 Chris Robshaw, 21 Karl Dickson, 22 Matt Hopper, 23 Ross Chisholm.
Sale Sharks v Leicester Tigers (3.15pm)
Sale show a number of changes from the side comprehensively beaten by Wasps last time out.
Flanker David Seymour captains a team that sees returns for Will Addison, Tommy Taylor, Sammy Tuitupou, Vadim Cobilas, Bryn Evans and Eifion Lewis Roberts, but centre Johnny Leota misses out due to suspension.
England Grand Slam trio Manu Tuilagi, Ben Youngs and Dan Cole will all start for Leicester, with Tuilagi partnering Owen Williams in midfield.
Youngs forges a half-back combination with Freddie Burns and Cole packing down alongside front-row colleagues Marcos Ayerza and Harry Thacker in a team captained by No 8 Jordan Crane.
Sale Sharks: 15 Mike Haley, 14 Will Addison, 13 Sam James, 12 Sammy Tuitupou, 11 Nev Edwards, 10 Danny Cipriani, 9 Peter Stringer; 1 Eifion Lewis-Roberts, 2 Tommy Taylor, 3 Vadim Cobilas, 4 Bryn Evans, 5 Jonathan Mills, 6 Cameron Neild, 7 David Seymour (c), 8 TJ Ioane.
Replacements: 16 Neil Briggs, 17 Ross Harrison, 18 Brian Mujati, 19 Andrei Ostrikov, 20 Magnus Lund, 21 James Mitchell, 22 Joe Ford, 23 Mark Jennings.
Leicester Tigers: 15 Tommy Bell, 14 Mathew Tait, 13 Manu Tuilagi, 12 Owen Williams, 11 Vereniki Goneva, 10 Freddie Burns, 9 Ben Youngs; 1 Marcos Ayerza, 2 Harry Thacker, 3 Dan Cole, 4 Dom Barrow, 5 Graham Kitchener, 6 Laurence Pearce, 7 Tom Croft, 8 Jordan Crane (c).
Replacements: 16 Greg Bateman, 17 Ellis Genge, 18 Fraser Balmain, 19 Sebastian de Chaves, 20 Opeti Fonua, 21 Sam Harrison, 22 Peter Betham, 23 Telusa Veainu.
