Harlequins v Leeds: Teams

Harlequins are forced into making two changes from the starting line-up that faced London Irish last week.

Scrum-half Danny Care picked up an ankle injury in the 35-27 victory over their capital rivals, so Simon Keogh gets the nod.

The other change sees England Sevens international Charlie Amesbury start on the left wing after Ugo Monye injured his back during training.

There are no changes to the pack, while on the bench Academy winger Seb Stegmann features in the Premiership squad for the first time.

Also amongst the replacements is Billy Fulton, who joined Quins on a short-term contract earlier this week.

Changes

Leeds director of rugby Stuart Lancaster has made five changes to his starting line-up for Saturday's Guinness Premiership match at Harlequins.

Alberto Di Bernardo and Hendre Fourie both suffered injuries in the opening day defeat to Gloucester, forcing Lancaster's hand.

Mark Lock replaces Fourie in the back row, with James Brooks coming in for Di Bernardo at fly-half.

New signing Adam Hopcroft makes his first appearance in the starting XV in place of Colin Noon in the front row.

John Holtby takes over from Tom Rock on the right wing and Leigh Hinton replaces Jon Goodridge at full back.

Goodridge and Lee Blackett face fitness tests before Leeds can confirm their replacements bench, which will include Vili Ma'asi and Erik Lund, who should make their first appearances for the club.

"We obviously lost Hendre Fourie and Alberto Di Bernardo last week and we are disappointed for both of them," said Lancaster.

"Hendre is making really good progress and hopefully he will be back sooner rather than later. However, their absence gives other people opportunities.

"James Brooks has shown great leadership in training, directing the team from fly-half, and he has plenty of experience of playing fly-half in the Guinness Premiership with Wasps and Northampton."

Harlequins team: 15 Mike Brown, 14 Tom Williams, 13 Hal Luscombe, 12 Jordan Turner-Hall, 11 Charlie Amesbury, 10 Chris Malone, 9 Simon Keogh; 1 Ceri Jones, 2 Aston Croall, 3 Mike Ross, 4 Ollie Kohn, 5 Jim Evans, 6 Chris Robshaw, 7 Paul Volley (Capt), 8 Tom Guest.

Replacements: 16 Christophe Laurent, 17 Ricky Nebbett, 18 Nicolas Spanghero, 19 Will Skinner, 20 Billy Fulton, 21 Tosh Masson, 22 Seb Stegmann.

Leeds: 15 Leigh Hinton, 14 John Holtby, 13 Jonny Hepworth, 12 Richard Welding, 11 Tom Biggs, 10 James Brooks, 9 Joe Bedford, 1 Michael Cusack, 2 Rob Rawlinson, 3 Adam Hopcroft, 4 Kearnan Myall, 5 Stuart Hooper, 6 Jon Dunbar, 7 Mark Lock, 8 Rhys Oakley.

Replacements: 16 Colin Noon, 17 Vili Ma'asi, 18 Erik Lund, 19 Sam Stitcher, 20 Mike Aspinall, 21 Lee Blackett, 22 Jon Goodridge.